Personal
Salvador Martínez Pérez
Group leader
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Neurobiology of mental, neurodegenerative and neuro-oncological diseases
https://in.umh-csic.es/group3885
- PROMETEO-STRUCTURAL AND FUNCTIONAL ALTERATIONS OF NEURONAL CIRCUITS IN THE CINGULATE AREA OF THE CEREBRAL CORTEX CAUSED BY DYSFUNCTION OF GENES INVOLVED IN BRAIN DISEASES
- Mecanismos fisiopatologicos de enfermedades cerebrales que actuan sobre el desarrollo de la corteza cerebral
- Chaperone mediated autophagy is deficient in spinal motoneurons of ALS patients with TDP-43 proteinopathy. Garrigos, D., Martinez-Morga, M., Pombero, A., García-Lopez, R., Pastor, D., Riquelme, D., Blanquer, M., Iniesta, F., Valdor, R., Geijo-Barrientos, E., Hargus, G., Moraleda, J.M and Martínez, S. Acta Neuropathologica Communications. 2026 14, 67 https://doi.org/10.1186/s40478-026-02238-6
- Chaperone-mediated autophagy sustains pericyte stemness necessary for brain tissue homeostasis. María Dolores Salinas ,Carlos M Martínez, Francisco J Roca,David García-Bernal, Marta Martínez-Morga , Juan R Rodríguez-Madoz,Felipe Prósper , Agustín G Zapata,Jose María Moraleda , Salvador Martínez , Rut Valdor. J Adv Res. 2026 80: 155-177, February 2026 https://doi.org/10.1016/j.jare.2025.04.015
- Futuro de la inteligencia: cerebro natural, cerebro artificial. Martínez-Morga, Marta; Garrigós, Daniel; Martínez, Salvador. Medicina (Buenos Aires) 2025 Medicina 85(Supl. I): 48-56 https://digital.csic.es/handle/10261/394256
- Safety and efficacy evaluation of intracerebroventricular human neural stem cell transplantation in SOD1 mice as a novel approach for ALS. Ivan Lombardi, Clelia Ferrero, Edvige Vulcano, Daniela Maria Rasà, Maurizio Gelati, Diego Pastor, Rose Mary Carletti, Silvia de la Morena, Daniela Celeste Profico, Sabrina Longobardi, Elisa Lazzarino, Elisa Perciballi, Jessica Diana Rosati, Salvador Martinez, Alessandro Vercelli, Angelo Luigi Vescovi, Marina Boido & Daniela Ferrari Journal of Translational Medicine. 2025 23: art. number: 529 (2025) https://doi.org/10.1186/s12967-025-06529-9
- Neurobiological basis of neonatal epilepsy and its comorbilities. Marta Martínez-Morga, Salvador J Martinez-Morga, Daniel Garrigos, Salvador Martinez. Medicina (B Aires). 2024 84 Suppl 1:2-8 https://pubmed.ncbi.nlm.nih.gov/38350617/
- Pericytes Are Immunoregulatory Cells in Glioma Genesis and Progression. Marta Martinez-Morga ,Daniel Garrigos, Elena Rodriguez-Montero, Ana Pombero, Raquel Garcia-Lopez, Salvador Martinez. Int. J. Mol. Sci. 2024 25(10), 5072 https://doi.org/10.3390/ijms25105072
- Selective vulnerability of motor neuron types and functional groups to degeneration in amyotrophic lateral sclerosis: review of the neurobiological mechanisms and functional correlates. Ovsepian, S.V., O’Leary, V.B. & Martinez, S. Brain Struct Funct . 2024 229: 1–14 https://doi.org/10.1007/s00429-023-02728-6
- The nuclei of human adult stem cells can move within the cell and generate cellular protrusions to contact other cells. Carlos Bueno, David García-Bernal, Salvador Martínez, Miguel Blanquer & José M. Moraleda. Stem Cell Research & Therapy. 2024 15: 32 (2024) https://doi.org/10.1186/s13287-024-03638-y
- ACE2 expression in the brain during development and susceptibility to brain infection by SARS-CoV-2. Marta Martínez-Morga ,Jose Manuel Hernandez-Lopez, Cristina Hernandez-Medina, Salvador Martínez-Morga, Salvador Martínez. Medicina (B Aires) 2023 83 Suppl 2:2-5. Spanish. PMID: 36820474 (Review)
- MAPK/MAK/MRK overlapping kinase (MOK) controls microglial inflammatory/type-I IFN responses via Brd4 and is involved in ALS Jesús A. Pérez-Cabello, Lucía Silvera-Carrasco,Jaime M. Franco, Vivian Capilla-González, Alexandros Armaos, María Gómez-Lima, Raquel García-García, Xin Wen Yap, Magdalena Leal-Lasarte, Deepti Lall, Robert H. Baloh, Salvador Martínez et al. PNAS 2023 120 (28); e2302143120 https://doi.org/10.1073/pnas.2302143120
- Neuronal progenitors of the dentate gyrus express the SARS‑CoV‑2 cell receptor during migration in the developing human hippocampus. Hernandez‑Lopez JM, Hernandez‑Medina C, Medina‑Corvalan C, Rodenas M, Almagro F, Perez‑Garcia C, Echevarria D, Carratala F, Geijo‑Barrientos E, Martinez S. Cellular and Molecular Life Sciences. 2023 80: art.140 https://doi.org/10.1007/s00018-023-04787-8
- Pericyte–Glioblastoma Cell Interaction: A Key Target to Prevent Glioblastoma Progression. Ana Pombero, Raquel Garcia-Lopez and Salvador Martínez Cells. 2023 12(9), art. 1324 https://doi.org/10.3390/cells12091324
- Abnormalities in Cortical GABAergic Interneurons of the Primary Motor Cortex Caused by Lis1 (Pafah1b1) Mutation Produce a Non-drastic Functional Phenotype. Domínguez-Sala E, Valdés-Sánchez L, Canals S, Reiner O, Pombero A, García-López R, Estirado A, Pastor D, Geijo-Barrientos E, Martínez S Front Cell Dev Biol. 2022 10: art 769853 https://doi.org/10.3389/fcell.2022.769853
- Adhesion molecule Amigo2 is involved in the fasciculation process of the fasciculus retroflexus. Company, V., Murcia-Ramón, R., Andreu-Cervera, A., Aracil-Pastor, P., Almagro-García, F., Martínez, S., Echevarría, D., Puelles, E. Dev Dyn. 2022 251(11): 1834-1847 https://doi.org/10.1002/dvdy.513
- Binucleated human bone marrow-derived mesenchymal cells can be formed during neural-like differentiation with independence of any cell fusion events. Bueno, C., Blanquer, M., García-Bernal, D., Martínez, S., Moraleda, J.M. Sci. Rep. 2022 12(1): art 20615 https://doi.org/10.1038/s41598-022-24996-8
- Chaperone-Mediated Autophagy Ablation in Pericytes Reveals New Glioblastoma Prognostic Markers and Efficient Treatment Against Tumor Progression. Molina, M.L., García-Bernal, D., Salinas, M.D., Rubio, G., Aparicio, P., Moraleda, J.M., Martínez, S., Valdor, R. Front Cell Dev Biol . 2022 10: art. 797945 https://doi.org/10.3389/fcell.2022.797945
- Editorial: What does human pathology bring to the understanding of the fundamental mechanisms of development? Represa, A., Martinez, S., Gelot, A. Front Neuroanat . 2022 16: art. 1003607 https://doi.org/10.3389/fnana.2022.1003607
- Gli2-Mediated Shh Signaling Is Required for Thalamocortical Projection Guidance Callejas-Marin A, Moreno-Bravo JA, Company V, Madrigal MP, Almagro-García F, Martínez S, Puelles E Frontiers in Neuroanatomy 2022 16: 830758 http://doi.org/10.3389/fnana.2022.830758
- Luis Puelles, the Learned Neuroembryologist and Comparative Neurobiologist. Martinez, S. Brain Behav Evol . 2022 96 (4-6): 167-173 Letter https://doi.org/10.1159/000522489
- Properties of the epileptiform activity in the cingulate cortex of a mouse model of LIS1 dysfunction Domínguez-Sala E, Andreu-Cervera A, Martín-Climent P, Murcia-Ramón R, Martínez S, Geijo-Barrientos E Brain Struct Funct 2022 227 (5): 1599-1614 https://doi.org/10.1007/s00429-022-02458-1
- Regenerative Neurology and Regenerative Cardiology: Shared Hurdles and Achievements. Mitrečić D, Hribljan V, Jagečić D, Isaković J, Lamberto F, Horánszky A, Zana M, Foldes G, Zavan B, Pivoriūnas A, Martinez S, Mazzini L, Radenovic L, Milasin J, Chachques JC, Buzanska L, Song MS, Dinnyés A Int J Mol Sci. 2022 23(2): 855 https://doi.org/10.3390/ijms23020855
- Shock wave and mesenchymal stem cells as treatment in the acute phase of spinal cord injury: A pilot study. Pastor D, Valera H, Olmo JA, Estirado A, Martínez S Rehabilitacion. 2022 56(1): 1-10 https://doi.org/10.1016/j.rh.2021.03.004
- Stria medullaris innervation follows the transcriptomic division of the habenula. Juárez-Leal, I., Carretero-Rodríguez, E., Almagro-García, F., Martínez, S., Echevarría, D., Puelles, E. Sci Rep. 2022 12(1): art 10118 https://doi.org/10.1038/s41598-022-14328-1
- The brain. An analogic machine with quantum functioning? Martínez-Morga M, Garrigós D, Martínez S Medicina (B Aires) 2022 82:2
- Differentiation of human adult-derived stem cells towards a neural lineage involves a dedifferentiation event prior to differentiation to neural phenotypes Bueno C, Martínez-Morga M, García-Bernal D, Moraleda JM, Martínez S Sci Rep 2021 11(1):12034 https://doi.org/10.1038/s41598-021-91566-9
- Interneuron Heterotopia in the Lis1 Mutant Mouse Cortex Underlies a Structural and Functional Schizophrenia-Like Phenotype Garcia-Lopez R, Pombero A, Estirado A, Geijo-Barrientos E, Martinez S Front Cell Dev Biol 2021 9:693919 https://doi.org/10.3389/fcell.2021.693919
- Netrin 1-Mediated Role of the Substantia Nigra Pars Compacta and Ventral Tegmental Area in the Guidance of the Medial Habenular Axons Company V, Andreu-Cervera A, Madrigal MP, Andrés B, Almagro-García F, Chédotal A, López-Bendito G, Martinez S, Echevarría D, Moreno-Bravo JA, Puelles E Front Cell Dev Biol 2021 9:682067 https://doi.org/10.3389/fcell.2021.682067
- Neurogenesis similarities in different human adult stem cells Bueno C, Martinez S Neural Regen Res 2021 16(1):123 https://doi.org/10.4103/1673-5374.286967
- Neurogenesis similarities in different human adult stem cells Bueno C, Martinez S Neural Regen Res 2021 16(1):123 https://doi.org/10.4103/1673-5374.286967
- The association of telomere length with substance use disorders: a systematic review and meta-analysis of observational studies Navarro-Mateu F, Husky M, Cayuela-Fuentes P, Álvarez FJ, Roca-Vega A, Rubio-Aparicio M, Chirlaque MD, Cayuela ML, Martínez S, Sánchez-Meca J Addiction 2021 116(8):1954 https://doi.org/10.1111/add.15312
- Autophagy in the Immunosuppressive Perivascular Microenvironment of Glioblastoma Molina ML, García-Bernal D, Martinez S, Valdor R Cancers (Basel) 2020 12(1):102 https://doi.org/10.3390/cancers12010102
- Birth-sex cohort alcohol use transitions in the general population: the cross-sectional PEGASUS-Murcia project Husky MM, Bharat C, Vilagut G, Salmerón D, Martínez S, Navarro C, Alonso J, Kessler RC, Navarro-Mateu F Adicciones 2020 32(2):94 https://doi.org/10.20882/adicciones.1067
- Combined intramuscular and intraspinal transplant of bone marrow cells improves neuromuscular function in the SOD1G93A mice Martínez-Muriana A, Pastor D, Mancuso R, Rando A, Osta R, Martínez S, López-Vales R, Navarro X Stem Cell Res Ther 2020 11(1):53 https://doi.org/10.1186/s13287-020-1573-6
- Gestational Exposure to Sodium Valproate Disrupts Fasciculation of the Mesotelencephalic Dopaminergic Tract, With a Selective Reduction of Dopaminergic Output From the Ventral Tegmental Area Ádám Á, Kemecsei R, Company V, Murcia-Ramón R, Juarez I, Gerecsei LI, Zachar G, Echevarría D, Puelles E, Martínez S, Csillag A Front Neuroanat 2020 14:29 https://doi.org/10.3389/fnana.2020.00029
- Intramuscular Injection of Bone Marrow Stem Cells in Amyotrophic Lateral Sclerosis Patients: A Randomized Clinical Trial. Geijo-Barrientos E, Pastore-Olmedo C, De Mingo P, Blanquer M, Gómez Espuch J, Iniesta F, Iniesta NG, García-Hernández A, Martín-Estefanía C, Barrios L, Moraleda JM, Martínez S Front Neurosci 2020 14:195 https://doi.org/10.3389/fnins.2020.00195
- Layer 2/3 Pyramidal Neurons of the Mouse Granular Retrosplenial Cortex and Their Innervation by Cortico-Cortical Axons Robles RM, Domínguez-Sala E, Martínez S, Geijo-Barrientos E Front Neural Circuits 2020 14:576504 https://doi.org/10.3389/fncir.2020.576504
- Mechanism of action of cell therapy in hereditary diseases Martinez-Morga M, Medina-Corvalan C, Perez-Garcia C, Bueno C, Martinez S Medicina (B. Aires) 2020 80 Suppl 2:2
- Neuronal tangential migration from Nkx2.1-positive hypothalamus Murcia-Ramón R, Company V, Juárez-Leal I, Andreu-Cervera A, Almagro-García F, Martínez S, Echevarría D, Puelles E Brain Struct Funct 2020 225(9):2857 https://doi.org/10.1007/s00429-020-02163-x
- Spanish Cell Therapy Network (TerCel): 15 years of successful collaborative translational research Sánchez-Guijo F, García-Olmo D, Prósper F, Martínez S, Zapata A, Fernández-Avilés F, Toledo-Aral JJ, Torres M, Fariñas I, Badimón L, Labandeira-García JL, García-Sancho J, Moraleda JM Cytotherapy 2020 22(1):1 https://doi.org/10.1016/j.jcyt.2019.11.001
- Childhood adversities and 5-HTTLPR polymorphism as risk factors of substance use disorders: retrospective case-control study in Murcia (Spain) Navarro-Mateu F, Quesada MP, Escámez T, Alcaráz MJ, Seiquer de la Peña C, Salmerón D, Huerta JM, Vilagut G, Chirlaque MD, Navarro C, Husky M, Kessler RC, Alonso J, Martínez S BMJ Open 2019 9(9):e030328 https://doi.org/10.1136/bmjopen-2019-030328
- Dopaminergic control of ADAMTS2 expression through cAMP/CREB and ERK: molecular effects of antipsychotics Ruso-Julve F, Pombero A, Pilar-Cuéllar F, García-Díaz N, Garcia-Lopez R, Juncal-Ruiz M, Castro E, Díaz Á, Vazquez-Bourgón J, García-Blanco A, Garro-Martinez E, Pisonero H, Estirado A, Ayesa-Arriola R, López-Giménez J, Mayor F Jr, Valdizán E, Meana J, Gonzalez-Maeso J, Martínez S, Vaqué JP, Crespo-Facorro B Proc Natl Acad Sci USA 2019 9(1):306 https://doi.org/10.1038/s41398-019-0647-7
- Glioblastoma ablates pericytes antitumor immune function through aberrant up-regulation of chaperone-mediated autophagy Valdor R, García-Bernal D, Riquelme D, Martinez CM, Moraleda JM, Cuervo AM, Macian F, Martinez S Proc Natl Acad Sci USA 2019 116(41):20655 https://doi.org/10.1073/pnas.1903542116
- Modification of the risk of post-traumatic stress disorder (PTSD) by the 5-HTTLPR polymorphisms after Lorca’s earthquakes (Murcia, Spain) Navarro-Mateu F, Escámez T, Quesada MP, Alcaráz MJ, Vilagut G, Salmerón D, Huerta JM, Chirlaque MD, Navarro C, Kessler RC, Alonso J, Martínez S Psychiatry Res 2019 282:112640 https://doi.org/10.1016/j.psychres.2019.112640
- Neurobiological bases of autism and cellular models for its experimental study Martínez-Morga M, Paz Quesada M, Bueno C, Martinez S Medicina 2019 79:27
- Non-proliferative neurogenesis in human periodontal ligament stem cells Bueno C, Martínez-Morga M, Martínez S Scientifc Reports 2019 9:18038 https://doi.org/10.1038/s41598-019-54745-3
- Radial glia fibers translate Fgf8 morphogenetic signals to generate a thalamic nuclear complex protomap in the mantle layer Botella-Lopez A, Garcia-Lopez R, Pombero A, Martinez S Brain Struct Funct 2019 224(2):661 https://doi.org/10.1007/s00429-018-1794-y
- Safety and Biodistribution of Human Bone Marrow-Derived Mesenchymal Stromal Cells Injected Intrathecally in Non-Obese Diabetic Severe Combined Immunodeficiency Mice: Preclinical Study Quesada MP, García-Bernal D, Pastor D, Estirado A, Blanquer M, García-Hernández AM, Moraleda JM, Martínez S Tissue Engineering and Regenerative Medicine 2019 16(5):525 https://doi.org/10.1007/s13770-019-00202-1
- Synaptic mechanisms underlying the intense firing of neocortical layer 5B pyramidal neurons in response to cortico-cortical inputs Sempere-Ferrandez A, Martinez S, Geijo-Barrientos E Brain Struct Funct 2019 224(4):1403 https://doi.org/10.1007/s00429-019-01842-8
- The association of telomere length with substance use disorders: systematic review and meta-analysis protocol Navarro-Mateu F, Rubio-Aparicio M, Cayuela P, Álvarez FJ, Roca-Vega A, Chirlaque MD, Cayuela ML, Husky M, Martínez S, Sánchez-Meca J Systematic Reviews 2019 8(1):298 https://doi.org/10.1186/s13643-019-1199-x
- Clinical Phenotypes Associated to Engrailed 2 Gene Alterations in a Series of Neuropediatric Patients Carratala-Marco F, Andreo-Lillo P, Martinez-Morga M, Escamez-Martinez T, Botella-Lopez A, Bueno C, Martinez S Front Neuroanat 2018 12:61 https://doi.org/10.3389/fnana.2018.00061
- Intramuscular transplantation of bone marrow cells prolongs the lifespan of SOD1(G93A) mice and modulates expression of prognosis biomarkers of the disease Rando A, Pastor D, Viso-Leon MC, Martinez A, Manzano R, Navarro X, Osta R, Martinez S Stem Cell Res Ther 2018 9:90 https://doi.org/10.1186/s13287-018-0843-z
- Neurobiological bases of autistic spectrum disorder and attention deficit hyperactivity disorder: neural differentiation and synaptogenesis Martinez-Morga M, Quesada-Rico MP, Bueno C, Martinez S Rev Neurol 2018 66:S97
- Prostaglandin EP2 Receptors Mediate Mesenchymal Stromal Cell-Neuroprotective Effects on Dopaminergic Neurons Parga JA, García-Garrote M, Martínez S, Raya Á, Labandeira-García JL, Rodríguez-Pallares J Mol Neurobiol 2018 55(6):4763 https://doi.org/10.1007/s12035-017-0681-5
- Vascular pattern of the dentate gyrus is regulated by neural progenitors Pombero A, Garcia-Lopez R, Estirado A, Martinez S Brain Struct Funct 2018 223(4):1971 https://doi.org/10.1007/s00429-017-1603-z
- Cancer and central nervous system disorders: protocol for an umbrella review of systematic reviews and updated meta-analyses of observational studies Catala-Lopez F, Hutton B, Driver JA, Page MJ, Ridao M,Valderas JM, Alonso-Arroyo A, Fores-Martos J, Martinez S, Genova-Maleras R, Macias-Saint-Gerons D, Crespo-Facorro B, Vieta E, Valencia A, Tabares-Seisdedos R Syst Rev 2017 6(1):69 https://doi.org/10.1186/s13643-017-0466-y
- Glioblastoma progression is assisted by induction of immunosuppressive function of pericytes through interaction with tumor cells Valdor R, Garcia-Bernal D, Bueno C, Rodenas M, Moraleda JM Macian F, Martinez S Oncotarget 2017 8(40):68614 https://doi.org/10.18632/oncotarget.19804
- Neuroplasticity: synaptogenesis during normal development and its implication in intellectual disability Martinez-Morga M, Martinez S Rev Neurol 2017 64:S45
- Post-Traumatic Stress Disorder and other mental disorders in the general population after Lorca’s earthquakes, 2011 (Murcia, Spain): A cross-sectional study Navarro-Mateu F, Salmeron D, Vilagut G, Tormo MJ, Ruiz-Merino G, Escamez T, Judez J, Martinez S, Koenen KC, Navarro C, Alonso J, Kessler RC PLoS One 2017 12(7):e0179690 https://doi.org/10.1371/journal.pone.0179690
- Brain development and plasticity Martinez-Morga M, Martinez S Rev Neurol 2016 62:S3
- Brain mesenchymal stem cells: physiology and pathological implications Pombero A, Garcia-Lopez R, Martinez S Dev Growth Differ 2016 58(5):469 https://doi.org/10.1111/dgd.12296
- Breathing pattern in a phase I clinical trial of intraspinal injection of autologous bone marrow mononuclear cells in patients with amyotrophic lateral sclerosis Ruiz-Lopez FJ, Guardiola J, Izura V, Gomez-Espuch J, Iniesta F, Blanquer M, Lopez-San Roman J, Saez V, De Mingo P, Martinez S, Moraleda JM Respir Physiol Neuro 2016 221:54 https://doi.org/10.1016/j.resp.2015.11.007
- Developmental guidance of the retroflex tract at its bending point involves Robo1-Slit2-mediated floor plate repulsion Moreno-Bravo JA, Martinez-Lopez JE, Madrigal MP, Kim M, Mastick GS, Lopez-Bendito G, Martinez S, Puelles E Brain Struct Funct 2016 221(1):665 https://doi.org/10.1007/s00429-014-0932-4
- Fgf15 regulates thalamic development by controlling the expression of proneural genes Martinez-Ferre A, Lloret-Quesada C, Prakash N, Wurst W, Rubenstein JL, Martinez S Brain Struct Funct 2016 221(6):3095 https://doi.org/10.1007/s00429-015-1089-5
- FoxP1 Protein Shows Differential Layer Expression in the Parahippocampal Domain among Bird Species Garcia-Calero E, Martinez S Brain Behav Evol 2016 87(4):242 https://doi.org/10.1159/000446601
- FoxP2 protein levels regulate cell morphology changes and migration patterns in the vertebrate developing telencephalon Garcia-Calero E, Botella-Lopez A, Bahamonde O, Perez-Balaguer A, Martinez S Brain Struct Funct 2016 221(6):2905 https://doi.org/10.1007/s00429-015-1079-7
- Intraventricular injections of mesenchymal stem cells activate endogenous functional remyelination in a chronic demyelinating murine model Cruz-Martinez P, Gonzalez-Granero S, Molina-Navarro MM, Pacheco-Torres J, Garcia-Verdugo JM, Geijo-Barrientos E, Jones J, Martinez S Cell Death Dis 2016 7:e2223 https://doi.org/10.1038/cddis.2016.130
- Mesencephalic origin of the rostral Substantia nigra pars reticulata Madrigal MP, Moreno-Bravo JA, Martinez-Lopez JE, Martinez S, Puelles E Brain Struct Funct 2016 221(3):1403 https://doi.org/10.1007/s00429-014-0980-9
- Preface to the special issue, Embryonic and adult neurogenesis in vertebrate’ Nakamura H, Martinez S Dev Growth Differ 2016 58(5):425 https://doi.org/10.1111/dgd.12304
- Rett Syndrome Mutant Neural Cells Lacks MeCP2 Immunoreactive Bands Bueno C, Tabares-Seisdedos R, Moraleda JM, Martinez S PLoS One 2016 11(4):e0153262 https://doi.org/10.1371/journal.pone.0153262
- Wnt1 signal determines the patterning of the diencephalic dorso-ventral axis Navarro-Garberi M, Bueno C, Martinez S Brain Struct Funct 2016 221(7):3693 https://doi.org/10.1007/s00429-015-1126-4
- Attractive Action of FGF-Signaling Contributes to the Postnatal Developing Hippocampus Cuccioli V, Bueno C, Belvindrah R, Lledo PM, Martinez S Hippocampus 2015 25(4):486 https://doi.org/10.1002/hipo.22386
- Developmental alterations of the septohippocampal cholinergic projection in a lissencephalic mouse model Garcia-Lopez R, Pombero A, Dominguez E, Geijo-Barrientos E, Martinez S Exp Neurol 2015 271:215 https://doi.org/10.1016/j.expneurol.2015.06.014
- Hairy/Enhancer-of-Split MEGANE and Proneural MASH1 Factors Cooperate Synergistically in Midbrain GABAergic Neurogenesis Wende CZ, Zoubaa S, Blak A, Echevarria D, Martinez S, Guillemot F, Wurst W, Guimera J PLoS One 2015 10(5):e0127681 https://doi.org/10.1371/journal.pone.0127681
- Mesencephalic basolateral domain specification is dependent on Sonic Hedgehog Martinez-Lopez JE, Moreno-Bravo JA, Madrigal MP, Martinez S, Puelles E Front Neuroanat 2015 9:12 https://doi.org/10.3389/fnen.2015.00012
- Mesenchymal Stem Cells Improve Motor Functions and Decrease Neurodegeneration in Ataxic Mice Jones J, Estirado A, Redondo C, Pacheco-Torres J, Sirerol-Piquer MS, Garcia-Verdugo JM, Martinez S Mol Ther 2015 23(1):130 https://doi.org/10.1038/mt.2014.143
- Novel aberrant genetic and epigenetic events in Friedreich’s ataxia Quesada MP, Jones J, Rodriguez-Lozano FJ, Moraleda JM, Martinez S Exp Cell Res 2015 335(1):51 https://doi.org/10.1016/j.yexcr.2015.04.013
- Red nucleus and rubrospinal tract disorganization in the absence of Pou4f1 Martinez-Lopez JE, Moreno-Bravo JA, Madrigal MP, Martinez S, Puelles E Front Neuroanat 2015 9:8 https://doi.org/10.3389/fnana.2015.00008
- The 2-subunit of the nicotinic cholinergic receptor is specifically expressed in medial subpallium-derived cells of mammalian amygdala Pombero A, Martinez S J Comp Neurol 2015 523(11):1608 https://doi.org/10.1002/cne.23754
- A High-Resolution Spatiotemporal Atlas of Gene Expression of the Developing Mouse Brain Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JLR, Wakeman WB, Hawrylycz MJ, Puelles L, Jones AR Neuron 2014 83(2):309 https://doi.org/10.1016/j.neuron.2014.05.033
- FGF8 activates proliferation and migration in mouse post-natal oligodendrocyte progenitor cells Cruz-Martinez P, Martinez-Ferre A, Jaramillo-Merchan J, Estirado A, Martinez S, Jones J PLoS One 2014 9(9):e108241 https://doi.org/10.1371/journal.pone.0108241
- Glioblastoma: a pathogenic crosstalk between tumor cells and pericytes Caspani EM, Crossley PH, Redondo-Garcia C, Martinez S PLoS One 2014 9(7):e101402 https://doi.org/10.1371/journal.pone.0101402
- Growth and differentiation factor 10 (Gdf10) is involved in Bergmann glial cell development under Shh regulation Mecklenburg N, Martinez-Lopez JE, Moreno-Bravo JA, Perez-Balaguer A, Puelles E, Martinez S Glia 2014 62(10):1713 https://doi.org/10.1002/glia.22710
- Interstitial deletion 14q223-q232: Genotype-phenotype correlation Martinez-Frias ML, Ocejo-Vinyals JG, Arteaga R, Martinez-Fernandez ML, Macdonald A, Perez-Belmonte E, Bermejo-Sanchez E, Martinez S Am J Med Genet A 2014 164(3):639 https://doi.org/10.1002/ajmg.a.36330
- Inverse and Direct Cancer Comorbidity in People with Central Nervous System Disorders: A Meta-Analysis of Cancer Incidence in 577,013 Participants of 50 Observational Studies Catala-Lopez F, Suarez-Pinilla M, Suarez-Pinilla P, Valderas JM, Gomez-Beneyto M, Martinez S, Balanza-Martinez V, Climent J, Valencia A,McGrath J, Crespo-Facorro B, Sanchez-Moreno J, Vieta E, Tabares-Seisdedor R Psychother Psychosom 2014 83(2):89 https://doi.org/10.1159/000356498
- Role of Shh in the development of molecularly characterized tegmental nuclei in mouse rhombomere 1 Moreno-Bravo JA, Perez-Balaguer A, Martinez-Lopez JE, Aroca P, Puelles L, Martinez S, Puelles E Brain Struct Funct 2014 219(3):777 https://doi.org/10.1007/s00429-013-0534-6
- Stem cell injection in the hindlimb skeletal muscle enhances neurorepair in mice with spinal cord injury Cruz-Martinez P, Pastor D, Estirado A, Pacheco-Torres J, Martinez S, Jones J Regen Med 2014 9(5):579 https://doi.org/10.2217/RME.14.38
- The cerebellum: from development to structural complexity and motor learning Martinez S Front Neuroanat 2014 8:118 https://doi.org/10.3389/fnana.2014.00118
- Acute and chronic MRI changes in the spine and spinal cord after surgical stem cell grafting in patients with definite amyotrophic lateral sclerosis: Post-infusion injuries are unrelated with clinical impairment Garcia-Santos JM, Blanquer M, Torres del Rio S, Iniesta F, Espuch JG, Perez-Espejo MT, Martinez S, Moraleda JM J Magn Reson Imaging 2013 31(8):1298 https://doi.org/10.1016/j.mri.2013.05.006
- Bone marrow transplantation in hindlimb muscles of motoneuron degenerative mice reduces neuronal death and improves motor function Pastor D, Viso-Leon MC, Botella-Lopez A, Jaramillo-Merchan J, Moraleda JM, Jones J, Martinez S Stem Cells Dev 2013 22(11):1633 https://doi.org/10.1089/scd.2012.0487
- Cellular and molecular basis of cerebellar development Martinez S, Andreu A, Mecklenburg N, Echevarria D Front Neuroanat 2013 7:18 https://doi.org/10.3389/fnana.2013.00018
- Differences in number and distribution of striatal calbindin medium spiny neurons between a vocal-learner (Melopsittacus undulatus) and a non-vocal learner bird (Colinus virginianus) Garcia-Calero E, Bahamonde O, Martinez S Front Neuroanat 2013 7:46 https://doi.org/10.3389/fnana.2013.00046
- Epidemiology and genetics of common mental disorders in the general population: the PEGASUS-Murcia project Navarro-Mateu F, Tormo M, Vilagut G, Alonso J, Ruiz-Merino G, Escamez T, Salmeron D, Judez J, Martinez S, Navarro C BMJ OPEN 2013 3(12):e004035 https://doi.org/10.1136/bmjopen-2013-004035
- Human adult periodontal ligament-derived cells integrate and differentiate after implantation into the adult mammalian brain Bueno C, Ramirez C, Rodriguez-Lozano FJ, Tabares-Seisdedos R, Rodenas M, Moraleda JM, Jones JR, Martinez S Cell Transplant 2013 22(11):2017 https://doi.org/10.3727/096368912X657305
- Mesenchymal stromal-cell transplants induce oligodendrocyte progenitor migration and remyelination in a chronic demyelination model Jaramillo-Merchan J, Jones J, Ivorra JL, Pastor D, Viso-Leon MC, Armengol JA, Molto MD, Geijo-Barrientos E, Martinez S Cell Death Dis 2013 4:e779 https://doi.org/10.1038/cddis.2013.304
- Roles of Wnt8a during formation and patterning of the mouse inner ear Vendrell V, Vazquez-Echevarria C, Lopez-Hernandez I, Alonso BD, Martinez S, Pujades C, Schimmang T Mech Dev 2013 130:160 https://doi.org/10.1016/j.mod.2012.09.009
- Stem Cells from Wildtype and Friedreich’s Ataxia Mice Present Similar Neuroprotective Properties in Dorsal Root Ganglia Cells Jones J, Estirado A, Redondo C, Martinez S PLoS One 2013 8(5):e62807 https://doi.org/10.1371/journal.pone.0062807
- Wnt signal specifies the intrathalamic limit and its organizer properties by regulating Shh induction in the alar plate Martinez-Ferre A, Navarro-Garberi M, Bueno C, Martinez S J Neurosci 2013 33(9):3967 https://doi.org/10.1523/JNEUROSCI.0726-12.2013
- Comparative Effects between Bone Marrow and Mesenchymal Stem Cell Transplantation in GDNF Expression and Motor Function Recovery in a Motorneuron Degenerative Mouse Model Pastor D, Viso-Leon MC, Jones J, Jaramillo-Merchan J, Toledo-Aral JJ, Moraleda JM, Martinez S Stem Cell Rev Rep 2012 8(2):445 https://doi.org/10.1007/s12015-011-9295-x
- Developmental dynamics of PAFAH1B subunits during mouse brain development Escamez T, Bahamonde O, Tabares-Seisdedos R, Vieta E, Martinez S, Echevarria D J Comp Neurol 2012 520(17):3877 https://doi.org/10.1002/cne.23128
- Fgf8-Related Secondary Organizers Exert Different Polarizing Planar Instructions along the Mouse Anterior Neural Tube Crespo-Enriquez I, Partanen J, Martinez S, Echevarria D PLoS ONE 2012 7(7):e39977 https://doi.org/10.1371/journal.pone.0039977
- Helios Transcription Factor Expression Depends on Gsx2 and Dlx1&2 Function in Developing Striatal Matrix Neurons Martin-Ibanez R, Crespo E, Esgleas M, Urban N, Wang B, Waclaw R, Georgopoulos K, Martinez S, Campbell K, Vicario-Abejon C, Alberch J, Chan S, Kastner P, Rubenstein JL, Canals JM Stem Cells Dev 2012 21(12):2239 https://doi.org/10.1089/scd.2011.0607
- Human adipose stem cell-conditioned medium increases survival of Friedreich’s ataxia cells submitted to oxidative stress Jones J, Estirado A, Redondo C, Bueno C, Martinez S Stem Cells Dev 2012 21(15):2817 https://doi.org/10.1089/scd.2012.0029
- Mesenchymal dental stem cells in regenerative dentistry Rodriguez-Lozano FJ, Insausti CL, Iniesta F, Blanquer M, Ramirez MC, Meseguer L, Meseguer-Henarejos AB, Marin N, Martinez S, Moraleda JM Med Oral Patol Oral Cir Bucal 2012 17(6):17925 https://doi.org/10.4317/medoral.17925
- Molecular Regionalization of the Developing Neural Tube Martinez S, Puelles E, Puelles L, EchevarriaD MOUSE NERVOUS SYSTEM 2012 p. 2 https://doi.org/10.1016/B978-0-12-369497-3.10001-9
- Molecular regionalization of the diencephalon Martinez-Ferre A, Martinez S Front Neurosci 2012 6:UNSP 73 https://doi.org/10.3389/fnins.2012.00073
- Neurotrophic Bone Marrow Cellular Nests Prevent Spinal Motoneuron Degeneration in Amyotrophic Lateral Sclerosis Patients: A Pilot Safety Study Blanquer M, Moraleda JM, Iniesta F, Gomez-Espuch J, Meca-Lallana J, Vilaverde R, Perez-Espejo MA, Ruiz-Lopez FJ, Santos JMG, Bleda P, Izura V,S aez M, De Mingo P, Vivancos L, Carles R, Jimenez J, Hernandez J, Guardiola J, Del Rio ST, Antunez C, De la Rosa P, MajadoMJ, Sanchez-Salinas A, Lopez J, Martinez-Lage JF, Martinez S Stem Cells 2012 30(6):1277 https://doi.org/10.1002/stem.1080
- Tissue Engineering with Dental Pulp Stem Cells: Isolation, Characterization, and Osteogenic Differentiation Rodriguez-Lozano FJ, Insausti CL, Meseguer L, Ramirez MC, Martinez S, Moraleda JM J Craniofac Surg 2012 23(6):E571 https://doi.org/10.1097/SCS.0b013e31825e4e16
- A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dolle P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A PLoS Biol 2011 9(1):e1000582 https://doi.org/10.1371/journal.pbio.1000582
- Cerebellar Oligodendroglial Cells have a Mesencephalic Origin Mecklenburg N, Garcia-Lopez R, Puelles E, Sotelo C, Martinez S Glia 2011 59(12):1946 https://doi.org/10.1002/glia.21236
- Mesenchymal stem cells derived from dental tissues Rodriguez-Lozano FJ, Bueno C, Insausti CL, Meseguer L, Ramirez MC, Blanquer M, Marin N, Martinez S, Moraleda JM Int Endod J 2011 44(9):800 https://doi.org/10.1111/j.1365-2591.2011.01877.x
- No paradox, no progress: inverse cancer comorbidity in people with other complex diseases Tabares-Seisdedos R, Dumont N, Baudot A, Valderas JM, Climent J, Valencia A, Crespo-Facorro B, Vieta E, Gomez-Beneyto M, Martinez S, Rubenstein JL Lancet Oncol 2011 12(6):604 https://doi.org/10.1016/S1470-2045(11)70041-9
- Pallial origin of basal forebrain cholinergic neurons in the nucleus basalis of Meynert and horizontal limb of the diagonal band nucleus Pombero A, Bueno C, Saglietti L, Rodenas M, Guimera J, Bulfone A, Martinez S Development 2011 138(19):4315 https://doi.org/10.1242/dev.069534
- Sprouty genes prevent excessive FGF signalling in multiple cell types throughout development of the cerebellum Yu T, Yaguchi Y, Echevarria D, Martinez S, Basson MA Development 2011 138(14):2957 https://doi.org/10.1242/dev.063784
- Thanatophoric Dysplasia Type II With Encephalocele and Semilobar Holoprosencephaly: Insights Into Its Pathogenesis Martinez-Frias ML, Egues X, Puras A, Hualde J, De Frutos CA, Bermejo E, Nieto MA, Martinez S Am J Med Genet A 2011 155A(1):197 https://doi.org/10.1002/ajmg.a.33765
- A surgical technique of spinal cord cell transplantation in amyotrophic lateral sclerosis Blanquer M, Perez-Espejo MA, Martinez-Lage JF, Iniesta F, Martinez S, Moraleda JM J Neurosci Methods 2010 191(2):255 https://doi.org/10.1016/j.jneumeth.2010.06.014
- Characterization of novel monoclonal antibodies able to identify neurogenic niches and arrest neurosphere proliferation and differentiation Del Valle I, Elvira G, Garcia-Benzaquen L, Armesilla-Diaz A, Kremer L, Garcia-Sanz JA, Martinez S, Silva A Neuroscience 2010 169(3):1473 https://doi.org/10.1016/j.neuroscience.2010.04.058
- Dynamic Expression Patterns of Nkx61 and Nkx62 in the Developing Mes-Diencephalic Basal Plate Moreno-Bravo JA, Perez-Balaguer A, Martinez S, Puelles E Dev Dynam 2010 239(7):2094 https://doi.org/10.1002/dvdy.22327
- Mesenchymal stem cells rescue Purkinje cells and improve motor functions in a mouse model of cerebellar ataxia Jones J, Jaramillo-Merchan J, Bueno C, Pastor D, Viso-Leon M, Martinez S Neurobiol Dis 2010 40(2):415 https://doi.org/10.1016/j.nbd.2010.07.001
- Molecular mechanisms controlling brain development: an overview of neuroepithelial secondary organizers Vieira C, Pombero A, Garcia-Lopez R, Gimeno D, Echevarria D, Martinez S Int J Dev Biol 2010 54(1):7 https://doi.org/10.1387/ijdb.092853cv
- Nolz1 promotes striatal neurogenesis through the regulation of retinoic acid signaling Urban N, Martin-Ibañez R, Herranz C, Esgleas M, Crespo E, Pardo M, Crespo-Enriquez I, Mendez-Gomez HR, Waclaw R, Chatzi C, Alvarez S, Alvarez R, Duester G, Campbell K, de Lera AR, Vicario-Abejon C, Martinez S, Alberch J, Canals JM Neural Dev 2010 5:21 https://doi.org/10.1186/1749-8104-5-21
- Oligodendrocyte Precursors Originate in the Parabasal Band of the Basal Plate in Prosomere 1 and Migrate into the Alar Prosencephalon During Chick Development Garcia-Lopez R, Martinez S Glia 2010 58(12):1437 https://doi.org/10.1002/glia.21019
Salvador Martínez Pérez