Personal
Salvador Sala Pla
Investigador Senior
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Transducción sensorial y nocicepción
https://in.umh-csic.es/grupo3906
- The ion channel TRPM8 is a direct target of the immunosuppressant rapamycin in primary sensory neurons. Arcas JM, Oudaha K, González A, Fernández-Trillo J, Peralta FC, Castro-Marsal J, Poyraz S, Tabener F, Sala S, de la Peña E, gomis A, Viana F. British Journal of Pharmacology. 2024 First published: 13 May 2024 https://doi.org/10.1111/bph.16402
- Natural Polyhydroxy Flavonoids, Curcuminoids, and Synthetic Curcumin Analogs as a7 nAChRs Positive Allosteric Modulators Ximenis M, Mulet J, Sala S, Sala F, Criado M, González-Muñiz R, Pérez de Vega MJ Int J Mol Sci 2021 22(2):973 https://doi.org/10.3390/ijms22020973
- 1-(2 ‘,5 ‘-Dihydroxyphenyl)-3-(2-fluoro-4-hydroxyphenyl)-1-propanone (RGM079): A Positive Allosteric Modulator of alpha 7 Nicotinic Receptors with Analgesic and Neuroprotective Activity Perez de Vega MJ, Fernandez-Mendivil C, de la Torre-Martinez R, Gonzalez-Rodriguez S, Mullet J, Sala F, Sala S, Criado M, Moreno-Fernandez S, Miguel M, Fernandez-Carvajal A, Ferrer-Montiel A, Lopez MG, Gonzalez-Muniz R ACS Chem Neurosci 2019 10(8):3900 https://doi.org/10.1021/acschemneuro.9b00364
- A Retino-retinal Projection Guided by Unc5c Emerged in Species with Retinal Waves Murcia-Belmonte V, Coca Y, Vegar C, Negueruela S, de Juan Romero C, Valiño AJ, Sala S, DaSilva R, Kania A, Borrell V, Martinez LM, Erskine L, Herrera E Current Biology 2019 29(7):1149 https://doi.org/10.1016/j.cub.2019.02.052
- Notch and EGFR regulate apoptosis in progenitor cells to ensure gut homeostasis in Drosophila Reiff T, Antonello ZA, Ballesta-Illán E, Mira L, Sala S, Navarro M, Martinez LM, Dominguez M EMBO Journal 2019 38(21):e101346 https://doi.org/10.15252/embj.2018101346
- Amino acid and peptide prodrugs of diphenylpropanones positive allosteric modulators of alpha 7 nicotinic receptors with analgesic activity Balsera B, Mulet J, Sala S, Sala F, de la Torre-Martinez R, Gonzalez-Rodriguez S, Plata A, Naesens L, Fernandez-Carvajal A, Ferrer-Montiel A, Criado M, Perez de Vega MJ, Gonzalez-Muniz R Eur J Med Chem 2018 143:157 https://doi.org/10.1016/j.ejmech.2017.https://doi.org/10.083
- Noise Maps for Quantitative and Clinical Severity Towards Long-Term ECG Monitoring Everss-Villalba E, Melgarejo-Meseguer FM, Blanco-Velasco M, Gimeno-Blanes FJ, Sala-Pla S, Rojo-alvarez JL, Garcia-Alberola A Sensors (Basel) 2017 17(11):2448 https://doi.org/10.3390/s17112448
- 1,3-diphenylpropan-1-ones as allosteric modulators of alpha 7 nACh receptors with analgesic and antioxidant properties Criado M, Balsera B, Mulet J, Sala S, Sala F, de la Torre-Martinez R, Fernandez-Carvajal A, Ferrer-Montiel A, Moreno-Fernandez S, Miguel M, Perez de Vega MJ, Gonzalez-Muñiz R Future Med Chem 2016 8(7):731 https://doi.org/10.4155/fmc-2015-0001
- N-Benzylpiperidine Derivatives as alpha 7 Nicotinic Receptor Antagonists Criado M, Mulet J, Sala F, Sala S, Colmena I, Gandia L, Bautista-Aguilera OM, Samadi A, Chioua M, Marco-Contelles J ACS Chem Neurosci 2016 7(8):1157 https://doi.org/10.1021/acschemneuro.6b00122
- Chalcones as positive allosteric modulators of alpha-7 nicotinic acetylcholine receptors: A new target for a privileged structure Balsera B, Mulet J, Fernandez-Carvajal A, Torre-Martinez Rde L, Ferrer-Montiel A, Hernandez-Jimenez JG, Estevez-Her, Borges R, Freitas AE, Lopez MG, Garcia-Lopez MT, Gonzalez-Muñiz R, Perez de Vega MJ, Valor LM, Svobodova L, Sala S, Sala F, Criado M Eur J Med Chem 2014 86:724 https://doi.org/10.1016/j.ejmech.2014.09.039
- Effect of triazine derivatives on neuronal nicotinic receptors Vazquez-Romero A, Criado M, Messeguer A, Vidal-Mosquera M, Mulet J, Sala F, Sala S ACS Chem Neurosci 2014 5(8):683 https://doi.org/10.1021/cn5000748
- Expression and functional properties of a7 acetylcholine nicotinic receptors are modified in the presence of other receptor subunits Criado M, Valor LM, Mulet J, Gerber S, Sala S, Sala F J Neurochem 2012 123(4):504 https://doi.org/10.1111/j.1471-4159.2012.07931.x
- A small cytoplasmic region adjacent to the fourth transmembrane segment of the alpha 7 nicotinic receptor is essential for its biogenesis Criado M, Mulet J, Gerber S, Sala S, Sala F FEBS Lett 2011 585(15):2477 https://doi.org/10.1016/j.febslet.2011.06.028
- Mutants of beta-strand beta 3 and the loop B in the interface between alpha 7 subunits of a homomeric acetylcholine receptor show functional and pharmacological alterations Criado M, Mulet J, Gerber S, Sala S, Sala F J Neurochem 2011 118(6):968 https://doi.org/10.1111/j.1471-4159.2011.07381.x
- Substitutions of amino acids in the pore domain of homomeric alpha 7 nicotinic receptors for analogous residues present in heteromeric receptors modify gating, rectification and binding properties Criado M, Svobodova L, Mulet J, Sala F, Sala S J Neurochem 2011 119(1):40 https://doi.org/10.1111/j.1471-4159.2011.07398.x
- Role of loop 9 on the function of neuronal nicotinic receptors Criado M, Castillo M, Mulet J, Sala F, Sala S BBA-Biomembranes 2010 1798(3):654 https://doi.org/10.1016/j.bbamem.2009.12.013
- Role of the extracellular transmembrane domain interface in gating and pharmacology of a heteromeric neuronal nicotinic receptor Aldea M, Castillo M, Mulet J, Sala S, Criado M, Sala F J Neurochem 2010 113(4):1036 https://doi.org/10.1111/j.1471-4159.2010.06665.x
- The loop between beta-strands beta 2 and beta 3 and its interaction with the N-terminal alpha-helix is essential for biogenesis of alpha 7 nicotinic receptors Criado M, Mulet J, Castillo M, Gerber S, Sala S, Sala F J Neurochem 2010 112(1):103 https://doi.org/10.1111/j.1471-4159.2009.06439.x
Salvador Sala Pla