Personal
José Vicente Sánchez Mut
Jefe de grupo
- Epi-Genómica Funcional del Envejecimiento y la Enfermedad de Alzheimer (URL: https://in.umh-csic.es/grupo3886)
- Bases genéticas y epigenéticas de la individualidad y el envejecimiento
- Plasticidad celular en enfermedad y reparación cerebral
- ALTERACIONES DE LA ENFERMEDAD DE ALZHEIMER CAUSADAS POR LA ACTIVIDAD NEURONAL
- CELULAR PLASTICITY IN AGEING
- NAAA TARGETS AND THERAPEUTIC MECHANISMS IN ALZHEIMER’S DISEASE
- Kdm1a safeguards the topological boundaries of PRC2-repressed genes and prevents aging-related euchromatinization in neurons. Del Blanco B, Niñerola S, Martín-González AM, Paraíso-Luna J, Kim M, Muñoz-Viana R, Racovac C, Sánchez-Mut JV, Ruan Y and Barco A. Nature Communications. 2024 15, 1781 (2024) https://www.nature.com/articles/s41467-024-45773-3
- A multiomic atlas of the aging hippocampus reveals molecular changes in response to environmental enrichment. Pérez, R.F., Tezanos, P., Peñarroya, A., González-Ramón, A., Urdinguio, R.G., Gancedo-Verdejo, J., Tejedor, J.R., Santamarina-Ojeda, P., Alba-Linares, J.J., Sainz-Ledo, L., Roberti, A., López, V., Mangas, C., Moro, M., Cintado, E., Muela, P., Rodríguez-Santamaría, M., Ortea, I., Iglesias-Rey, R., Castilla-Silgado, J., Tomás-Zapico, C., Iglesias-Gutiérrez, E., Sanchez-Mut, J.V., Trejo, J.L., Fernández, A.F. and Fraga, M.F. Nature Communications. 2024 15, art. 5829 https://www.nature.com/articles/s41467-024-49608-z#citeas
- Synaptic and extrasynaptic distribution of NMDA receptors in the cortex of Alzheimer’s disease patients. Escamilla S, Badillos R, Comella JX, Solé M, Pérez-Otaño I, Sánchez Mut JV, Sáez-Valero J and Cuchillo-Ibáñez I. Alzheimer's & Dementia 2024 1-15 (in press) https://doi.org/10.1002/alz.14125
- PM20D1 is a quantitative trait locus associated with Alzheimer’s disease Sanchez-Mut JV,Heyn H, Silva BA, Dixsaut L, Garcia-Esparcia P, Vidal E, Sayols S, Glauser L, Monteagudo-Sánchez A, Perez-Tur J, Ferrer I, Monk D, Schneider B, Esteller M, Gräff Nat Med 2018 24(5):598 https://doi.org/10.1038/s41591-018-0013-y
- Human DNA methylomes of neurodegenerative diseases show common epigenomic patterns Sanchez-Mut JV,Heyn H, Vidal E, Moran S, Sayols S, Delgado-Morales R, Schultz MD, Ansoleaga B Garcia-Esparcia P, Pons-Espinal M, Martinez de Lagran M, Dopazo J, Rabano A, Avila J, Dierssen M, Ira Lott, Ferrer I, Ecker JR, Esteller M Transl Psychiatry 2016 6(1):e718 https://doi.org/10.1038/tp.2015.214
- Epigenetic Alterations in Alzheimer’s Disease. Sanchez-Mut JV , Gräff J. Front Behav Neurosci 2015 0,6159722222 https://doi.org/10.3389/fnbeh.2015.00347
- Promoter hypermethylation of the phosphatase DUSP22 mediates PKA-dependent TAU phosphorylation and CREB activation in Alzheimer’s disease Jose Vicente Sanchez-Mut , Ester Aso, Holger Heyn, Tadashi Matsuda, Christoph Bock, Isidre Ferrer, Manel Esteller Hippocampus 2014 24(4):363 https://doi.org/ 10.1002/hipo.22245
- DNA methylation map of mouse and human brain identifies target genes in Alzheimer’s disease Jose V Sanchez-Mut , Ester Aso, Nicolas Panayotis, Ira Lott, Mara Dierssen, Alberto Rabano, Rocio G Urdinguio, Agustin F Fernandez, Aurora Astudillo, Jose I Martin-Subero, Balazs Balint, Mario F Fraga, Antonio Gomez, Cecile Gurnot, Jean-Christophe Roux, Jesus Avila, Takao K Hensch, Isidre Ferrer, Manel Esteller Brain 2013 136(Pt 10):3018 https://doi.org/10.1093/brain/awt237
José Vicente Sánchez Mut