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Isabel Pérez Otaño
Investigador principal
- Desarrollo, refinamiento y consolidación de circuitos neuronales (URL: https://in.umh-csic.es/grupo3894)
- Modulación sináptica de los circuitos neuronales y la conducta
- Synaptic modulation of neural circuits and behavior
- Juvenile NMDA receptors: a cellular and circuit perspective
- DEciphering mechanisms of presynaptic refinement
- Beyond the synapse: juvenile NMDARs in the configuration of neural circuits and dissection of underlying mechanisms
- Ayudas Extraordinarias CSIC
- Receptores NMDA No-Convencionales: Estudios a Nivel Celular y de Circuitos Neuronales
- Control of protein synthesis and memory by GluN3A-NMDA receptors through inhibition of GIT1/mTORC1 assembly. Conde-Dusman MJ, Dey PN, Elía-Zudaire Ó, Rabaneda LG, García-Lira C, Grand T, Briz V, Velasco ER, Andero R, Niñerola S, Barco A, Paoletti P, Wesseling JF, Gardoni F, Tavalin SJ, Perez-Otaño I eLife 2021 10:e71575 https://doi.org/10.7554/eLife.71575
- Elevated synaptic vesicle release probability in synaptophysin/gyrin family quadruple knockouts Raja MK, Preobraschenski J, Del Olmo-Cabrera S, Martinez-Turrillas R, Jahn R, Perez-Otano I, Wesseling JF eLife 2019 8:e40744 https://doi.org/10.7554/eLife.40744
- Emerging roles of GluN3-containing NMDA receptors in the CNS Perez-Otaño I, Larsen RS, Wesseling JF Nat Rev Neurosci 2016 17(10):623 https://doi.org/10.1038/nrn.2016.92
- GluN3A expression restricts spine maturation via inhibition of GIT1/Rac1 signaling Maria Fiuza, Immaculada González-González, and Isabel Pérez-Otaño PNAS 2013 110(51): 20807 https://doi.org/10.1073/pnas.1312211110
- GluN3A NMDA receptor subunits: more enigmatic than ever? Crawley O, Conde-Dusman MJ,Perez-Otano I J Physiol (London) 2022 600(2):261 https://doi.org/10.1113/JP280879
- Presynaptic NMDARs and astrocytes ally to control circuit-specific information flow Perez-Otano I, Rodriguez-Moreno A Proc Natl Acad Sci USA 2019 116(27):13166 https://doi.org/10.1073/pnas.1908293116
- RNAi-Based GIuN3A Silencing Prevents and Reverses Disease Phenotypes Induced by Mutant huntingtin Marco S, Murillo A, Pérez-Otaño I Mol Ther 2018 26(8):1965 https://doi.org/10.1016/j.ymthe.2018.05.013
- Sparse force-bearing bridges between neighboring synaptic vesicles Wesseling JF, Phan S, Bushong EA, Siksou L, Marty S, Pérez-Otaño I, Ellisman M Brain Struct Funct 2019 224(9):3263 https://doi.org/10.1007/s00429-019-01966-x
- Temporal Dynamics and Neuronal Specificity of Grin3a Expression in the Mouse Forebrain Murillo A, Navarro AI, Puelles E, Zhang Y, Petros TJ, Pérez-Otaño I Cereb Cortex 2021 31(4):1914 https://doi.org/10.1093/cercor/bhaa330
Isabel Pérez Otaño