Oliver Crawley undertook his PhD with Dr. Enrique Martinez-Perez at Imperial College London where he studied how chromosome cohesion is regulated during meiosis. He continued using C. elegans imaging during his postdoctoral work with Prof. Brock Grill at Scripps Florida to identify genetic pathways determining axonal and presynaptic development. His work helped uncover how autophagy is controlled in the distal axon via ubiquitination of UNC-51/ULK1. His current research in Prof. Isabel Pérez-Otaño´s group at the Instituto de Neurociencias de Alicante, funded by Severo-Ochoa and Marie-Curie fellowships, is revealing how NMDA receptors influence axonal morphology during circuit refinement in the mouse brain.
- Desarrollo, refinamiento y consolidación de circuitos neuronales (URL: https://in.umh-csic.es/grupo3894)
- Autophagy in axonal and presynaptic development Crawley O, Grill B Curr Opin Neurobiol 2021 69:139 https://doi.org/10.1016/j.conb.2021.03.011