Personal
Hugo Cabedo Martí
Investigador principal
- Control molecular de la mielinización axonal (URL: https://in.umh-csic.es/grupo3879)
- Neurobiología del dolor y la inflamación
- Investigación traslacional de las enfermedades neurológicas y psiquiátricas
- A genetic compensatory mechanism regulated by Jun and Mef2d modulates the expression of distinct class IIa Hdacs to ensure peripheral nerve myelination and repair Velasco-Aviles S, Patel N, Casillas-Bajo A, Frutos-Rincón L, Velasco E, Gallar J, Arthur-Farraj P, Gomez-Sanchez JA, Cabedo H eLife 2022 11:e72917 https://doi.org/10.7554/eLife.72917
- Emerging Role of HDACs in Regeneration and Ageing in the Peripheral Nervous System: Repair Schwann Cells as Pivotal Targets. Gomez-Sanchez JA, Patel N, Martirena F, Fazal SV, Mutschler C, Cabedo H. Int J Mol Sci. 2022 23(6): art 2996 - Review https://doi.org/10.3390/ijms23062996
- Fasciclin 2 engages EGFR in an auto-stimulatory loop to promote imaginal disc cell proliferation in Drosophila. Velasquez E, Gomez-Sanchez JA, Donier E, Grijota-Martinez C, Cabedo H, Garcia-Alonso L PLoS Genet. 2022 18(6): art. e1010224 https://doi.org/10.1371/journal.pgen.1010224
- Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun Wagstaff LJ, Gomez-Sanchez JA, Fazal SV, Otto GW, Kilpatrick AM, Michael K, Wong LY, Ma KH, Turmaine M, Svaren J, Gordon T, Arthur-Farraj P, Velasco-Aviles S, Cabedo H, Benito C, Mirsky R, Jessen KR eLife 2021 10:e62232 https://doi.org/10.7554/eLife.62232
- Novel EGR2 variant that associates with Charcot-Marie-Tooth disease when combined with lipopolysaccharide-induced TNF-alpha factor T49M polymorphism Blanco-Cantó ME, Patel N, Velasco-Aviles S, Casillas-Bajo A, Salas-Felipe J, García-Escrivá A, Díaz-Marín C, Cabedo H Neurol Genet 2020 6(2):e407 https://doi.org/10.1212/NXG.0000000000000407
- Class IIa HDACs in myelination Velasco-Aviles S, Gomez-Sanchez JA, Cabedo H Aging-US 2018 10(5):853 https://doi.org/10.18632/aging.101443
- Class IIa histone deacetylases link cAMP signaling to the myelin transcriptional program of Schwann cells Gomis-Coloma C, Velasco-Aviles S, Gomez-Sanchez JA, Casillas-Bajo A, Backs J, Cabedo H J Cell Biol 2018 217(4):1249 https://doi.org/10.1083/jcb.201611150
- Epigenetic induction of the Ink4a/Arf locus prevents Schwann cell overproliferation during nerve regeneration and after tumorigenic challenge Gomez-Sanchez JA, Gomis-Coloma C, Morenilla-Palao C, Peiro G, Serra E, Serrano M, Cabedo H Brain 2013 136:2262 https://doi.org/10.1093/brain/awt130
- L1CAM binds ErbB receptors through Ig-like domains coupling cell adhesion and neuregulin signalling Donier E, Gomez-Sanchez JA, Grijota-Martinez C, Lakoma J, Baars S, Garcia-Alonso L, Cabedo H PLoS ONE 2012 7(7):e40674 https://doi.org/10.1371/journal.pone.0040674
Hugo Cabedo Martí