Personal
Berta López Sánchez-Laorden
Investigador principal
- Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease. Sánchez-Laorden B*, López-Blau C, De Frutos CA, Boutet A, Arévalo M, Rowe RG, Weiss SJ, López-Novoa JM, Nieto MA. Nature Medicine 2015 21(9): 989- 97
- The immune-microenvironment confers resistance to MAP kinase pathway inhibitors through macrophage-derived TNFα. Sanchez-Laorden B* , O'Brien K, Brunton H, Ferguson J, Young H, Dhomen N, Flaherty KH, Frederick DT , Cooper ZA, Wargo JA, Marais R and Wellbrock C. Cancer Discovery 2014 4(10): 1214- 29
- Ultraviolet radiation accelerates BRAF-driven melanomagenesis by targeting TP53. Sanchez-Laorden B*, Pedersen M, Furney SJ, Rae J, Hogan K, Ejiama S, Girotti MR, Cook M, Dhomen N, Marais R. Nature 2014 511(7510): 478- 82
- MEK/ERK pathway reactivation drives invasion and metastasis in drug-resistant melanoma. Viros A, Girotti MR, Pedersen M, Saturno G, Zambon A, Niculescu-Duvaz D, Turajlic S, Hayes A, Gore M, Larkin J, Lorigan P, Cook M, Springer C, Marais R. Science Signaling 2014 7(318): ra- 30
- Regulation of human melanocortin 1 receptor signaling and trafficking by Thr-308 and Ser-316 and its alteration in variant alleles associated with red hair and skin cancer. Jimenez-Cervantes C, Garcia-Borron JC. J Biol Chem 2007 282(5): 3241- 5
Berta López Sánchez-Laorden