Skip to content
Accelerated epigenetic aging in Huntington’s disease involves polycomb repressive complex 1.
111641
Baptiste Brulé, Rafael Alcalá-Vida, Noémie Penaud, Jil Scuto, Coline Mounier, Jonathan Seguin, Sina Vincent Khodaverdian, Brigitte Cosquer, Etienne Birmelé, Stéphanie Le Gras, Charles Decraene, Anne-Laurence Boutillier & Karine Merienne
111641
Nature Communications.
111641
2025
111641
16, Article number: 1550 (2025)
111641
https://doi.org/10.1038/s41467-025-56722-z
Keep calm and carry H3K27me1 off.
100753
Alcalá-Vida R, Barco A.
100753
Neuron
100753
2024
100753
112(17): 2829-2832
100753
https://doi.org/10.1016/j.neuron.2024.07.014
Dysregulated expression of cholesterol biosynthetic genes in Alzheimer’s disease alters epigenomic signatures of hippocampal neurons.
100771
Paiva I, Seguin J, Grgurina I, Singh AK, Cosquer B, Plassard D, Tzeplaeff L, Le Gras S, Cotellessa L, Decraene C, Gambi J, Alcala-Vida R, Eswaramoorthy M, Buée L, Cassel JC, Giacobini P, Blum D, Merienne K, Kundu TK, Boutillier AL.
100771
Neurobiol Dis.
100771
2024
100771
198: 106538
100771
https://doi.org/10.1016/j.nbd.2024.106538
Mutant FUS induces chromatin reorganization in the hippocampus and alters memory processes.
100780
Tzeplaeff L, Seguin J, Le Gras S, Megat S, Cosquer B, Plassard D, Dieterlé S, Paiva I, Picchiarelli G, Decraene C, Alcala-Vida R, Cassel JC, Merienne K, Dupuis L, Boutillier AL.
100780
Prog Neurobiol.
100780
2023
100780
227: 102483
100780
https://doi.org/10.1016/j.pneurobio.2023.102483
Altered activity-regulated H3K9 acetylation at TGF-beta signaling genes during egocentric memory in Huntington’s disease.
100789
Alcalá-Vida R, Lotz C, Brulé B, Seguin J, Decraene C, Awada A, Bombardier A, Cosquer B, Pereira de Vasconcelos A, Brouillet E, Cassel JC, Boutillier AL, Merienne K.
100789
Prog Neurobiol.
100789
2022
100789
219: 102363
100789
https://doi.org/10.1016/j.pneurobio.2022.102363
Altered m6A RNA methylation contributes to hippocampal memory deficits in Huntington’s disease mice.
100798
Pupak A, Singh A, Sancho-Balsells A, Alcalá-Vida R, Espina M, Giralt A, Martí E, Ørom UAV, Ginés S, Brito V.
100798
Cell Mol Life Sci.
100798
2022
100798
79(8): 416
100798
https://doi.org/10.1007/s00018-022-04444-6
Hippocampal Cannabinoid 1 Receptors Are Modulated Following Cocaine Self-administration in Male Rats.
100807
De Sa Nogueira D, Bourdy R, Alcala-Vida R, Filliol D, Andry V, Goumon Y, Zwiller J, Romieu P, Merienne K, Olmstead MC, Befort K.
100807
Mol Neurobiol.
100807
2022
100807
59(3): 1896-1911
100807
https://doi.org/10.1007/s12035-022-02722-9
Age-related and disease locus-specific mechanisms contribute to early remodelling of chromatin structure in Huntington’s disease mice.
100816
Alcalá-Vida R, Seguin J, Lotz C, Molitor AM, Irastorza-Azcarate I, Awada A, Karasu N, Bombardier A, Cosquer B, Skarmeta JLG, Cassel JC, Boutillier AL, Sexton T, Merienne K.
100816
Nat Commun.
100816
2021
100816
12(1): 364
100816
https://doi.org/10.1038/s41467-020-20605-2
Neuron type-specific increase in lamin B1 contributes to nuclear dysfunction in Huntington’s disease.
100825
Alcalá-Vida R, Garcia-Forn M, Castany-Pladevall C, Creus-Muncunill J, Ito Y, Blanco E, Golbano A, Crespí-Vázquez K, Parry A, Slater G, Samarajiwa S, Peiró S, Di Croce L, Narita M, Pérez-Navarro E.
100825
EMBO Mol Med.
100825
2021
100825
13(2): e12105
100825
https://doi.org/10.15252/emmm.202012105
Epigenetic mechanisms underlying enhancer modulation of neuronal identity, neuronal activity and neurodegeneration.
100834
Alcalà-Vida R, Awada A, Boutillier AL, Merienne K.
100834
Neurobiol Dis.
100834
2021
100834
147: 105155
100834
https://doi.org/10.1016/j.nbd.2020.105155
Ver otros años
English