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A novel proneural function of Asense is integrated with the sequential actions of Delta-Notch, L’sc and Su(H) to promote the neuroepithelial to neuroblast transition.
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Mercedes Martin,Francisco Gutierrez-Avino,Mirja N. Shaikh,Francisco J. Tejedor
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PLos Genet.
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2023
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19(10): e1010991
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https://doi.org/10.1371/journal.pgen.1010991
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Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease.
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Viard , Yann Loe-Mie, Rachel Daudin , Malik Khelfaoui , Christine Plancon, Anne Boland, Tejedor FJ et al.
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Life Sci Alliance .
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2022
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5 (12) : art e202101205
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https://doi.org/10.26508/lsa.202101205
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Mnb/Dyrk1A orchestrates a transcriptional network at the transition from self-renewing neurogenic progenitors to postmitotic neuronal precursors
34644
Shaikh MN, Tejedor FJ
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J Neurogen
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2018
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32(1):37
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https://doi.org/10.1080/01677063.2018.1438427
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Minibrain drives the Dacapo-dependent cell cycle exit of neurons in the Drosophila brain by promoting asense and prospero expression
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Shaikh MN, Gutierrez-Aviño F, Colonques J, Ceron J, Hämmerle B, Tejedor FJ
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Development
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2016
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143(17):3195
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https://doi.org/10.1242/dev.134338
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DYRK1A: A Potential Drug Target for Multiple Down Syndrome Neuropathologies
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Becker W, Soppa U, Tejedor FJ
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CNS Neurol Disord-Drug Targets
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2014
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13(1):26
35508
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The Down syndrome-related protein kinase DYRK1A phosphorylates p27(Kip1) and Cyclin D1 and induces cell cycle exit and neuronal differentiation
35649
Soppa U, Schumacher J, Florencio V, Pasqualon T, Tejedor FJ, Becker W
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Cell Cycle
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2014
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13(13):2084
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https://doi.org/10.4161/cc.29104
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A Transient Expression of Prospero Promotes Cell Cycle Exit of Drosophila Postembryonic Neurons through the Regulation of Dacapo
36171
Colonques J, Ceron J, Reichert H, Tejedor FJ
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PLoS ONE
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2011
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6(4):e19342
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https://doi.org/10.1371/journal.pone.0019342
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MNB/DYRK1A as a multiple regulator of neuronal development
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Tejedor FJ, Hammerle B
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FEBS J
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2011
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278(2):223
36288
https://doi.org/10.1111/j.1742-4658.2010.07954.x
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Transient expression of Mnb/Dyrk1a couples cell cycle exit and differentiation of neuronal precursors by inducing p27(KIP1) expression and suppressing NOTCH signaling
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Hammerle B, Ulin E, Guimera J, Becker W, Guillemot F, Tejedor FJ
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Development
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2011
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138(12):2543
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https://doi.org/10.1242/dev.066167
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Local translation of dendritic RhoA revealed by an improved synaptoneurosome preparation
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Troca-Marin JA, Alves-Sampaio A, Tejedor FJ, Montesinos ML
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Mol Cell Neurosci
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2010
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43(3):308
36483
https://doi.org/10.1016/j.mcn.2009.12.004
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