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Intrinsically disordered intracellular domains control key features of the mechanically-gated ion channel PIEZO2.
33654
Verkest, C., Schaefer, I., Nees, T.A., Wang, N., Jegelka, J.M., Taberner, F.J., Lechner, S.G.
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Nature Communications
33654
2022
33654
13(1): art. 1365
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http://doi.org/10.1038/s41467-022-28974-6
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Neuropathic pain caused by miswiring and abnormal end organ targeting.
51244
Gangadharan V, Zheng H, Taberner FJ, Landry J, Nees TA, Pistolic J, Agarwal N, Männich D, Benes V, Helmstaedter M, Ommer B, Lechner SG, Kuner T, Kuner R.
51244
Nature.
51244
2022
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606 (7912): 137-145
51244
https://doi.org/10.1038/s41586-022-04777-z
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Identification of a population of peripheral sensory neurons that regulates blood pressure
33810
Morelli C,Castaldi L, Brown SJ, Streich LL, Websdale A, Taberner FJ, Cerreti B, Barenghi A, Blum KM, Sawitzke J, Frank T, Steffens LK, Doleschall B, Serrao J, Ferrarini D, Lechner SG, Prevedel R, Heppenstall PA.
33810
Cell Reports
33810
2021
33810
35(9)
33810
https://doi.org/10.1016/j.celrep.2021.109191
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USH2A is a Meissner’s corpuscle protein necessary for normal vibration sensing in mice and humans
33957
Schwaller F , Bégay V, García-García G, Taberner FJ, Moshourab R, McDonald B, Docter T, Kühnemund J, Ojeda-Alonso J, Paricio-Montesinos R, Lechner SG, Poulet JFA, Millan JM, Lewin GR
33957
Nat Neurosci
33957
2021
33957
24(1):74
33957
https://doi.org/10.1038/s41593-020-00751-y
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SUMOylation of Enzymes and Ion Channels in Sensory Neurons Protects against Metabolic Dysfunction, Neuropathy, and Sensory Loss in Diabetes
34149
Agarwal N , Taberner FJ, Rangel Rojas D, Moroni M, Omberbasic D, Njoo C, Andrieux A, Gupta P, Bali KK, Herpel E, Faghihi F, Fleming T, Dejean A, Lechner SG, Nawroth PP, Lewin GR, Kuner R.
34149
Neuron
34149
2020
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107(6):1141
34149
https://doi.org/10.1016/j.neuron.2020.06.037
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Structure-guided examination of the mechanogating mechanism of PIEZO2
34419
Taberner FJ,Prato V, Schaefer I, Schrenk-Siemens K, Heppenstall PA, Lechner SG
34419
Proc Natl Acad Sci USA
34419
2019
34419
116(28):14260
34419
https://doi.org/10.1073/pnas.1905985116
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Hyaluronan modulates TRPV1 channel opening, reducing peripheral nociceptor activity and pain
35322
Caires R, Luis E, Taberner FJ, Fernandez-Ballester G, Ferrer-Montiel A, Balazs EA, Gomis A, Belmonte C, De la Peña E
35322
Nat Commun
35322
2015
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6:8095
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https://doi.org/10.1038/ncomms9095
English