Personal
Khalil Kass Youssef
Investigador emergente
- Plasticidad Celular en Desarrollo y Enfermedad (URL: https://in.umh-csic.es/grupo3902)
- Epithelial–mesenchymal transition in tissue repair and degeneration. Youssef, K.K. and Nieto, M.A. Nat. Rev. Mol. Cell. Biol. 2024 25, 720-739 https://doi.org/10.1038/s41580-024-00733-z
- Two distinct Epithelial to Mesenchymal Transition Programmes Control Invasion and Inflammation in Segregated Tumour Cell Populations. Kass Youssef, K., Narwade, N., Arcas, A., Marquez-Galera, A., Jiménez, R., Lopez-Blau, C., Fazilaty, H., García-Gutierrez, D., Cano, A., Galcerán, J., Moreno-Bueno, G., Lopez-Atalaya, J.P. and Nieto, M.A. Nature Cancer. 2024 https://doi.org/10.1038/s43018-024-00839-5
- Defining microRNA signatures of hair follicular stem and progenitor cells in healthy and androgenic alopecia patients Mohammadi P, Nilforoushzadeh MA, Youssef KK, Sharifi-Zarchi A, Moradi S, Khosravani P, Aghdami R, Taheri P, Hosseini Salekdeh G, Baharvand H, Aghdami N J Dermatol Sci 2021 101(1):49 https://doi.org/10.1016/j.jdermsci.2020.11.002
- Glucose Metabolism Takes Center Stage in Epithelial-Mesenchymal Plasticity Kass Youssef K, Nieto MA Dev Cell. 2020 53(2):133 https://doi.org/10.1016/j.devcel.2020.03.021
- A gene regulatory network to control EMT programs in development and disease Fazilaty H, Rago L, Kass Youssef K, Ocaña OH, Garcia-Asencio F, Arcas A, Galceran J, Nieto MA Nat Comm. 2019 10:5115 https://doi.org/10.1038/s41467-019-13091-8
- Defining the clonal dynamics leading to mouse skin tumour initiation. Sánchez-Danés A, Hannezo E, Larsimont JC, Liagre M, Youssef KK, Simons BD, and Blanpain C. Nature. 2016 536: 298–303 https://doi.org/10.1038/nature19069
- Sox9 Controls Self-Renewal of Oncogene Targeted Cells and Links Tumor Initiation and Invasion. Larsimont JC, Youssef KK, Sánchez-Danés A, Sukumaran V, Defrance M, Delatte B, Liagre M, Baatsen P, Marine JC, et al. Cell Stem Cell. 2015 17: 60 - 73 https://doi.org/10.1016/j.stem.2015.05.008
- Adult interfollicular tumour-initiating cells are reprogrammed into an embryonic hair follicle progenitor-like fate during basal cell carcinoma initiation. Youssef KK, Lapouge G, Bouvrée K, Rorive S, Brohée S, Appelstein O, Larsimont JC, Sukumaran V, Van de Sande B, Pucci D, Dekoninck S, Berthe JV, Aerts S, Salmon I, Del Marmol V, Blanpain C. Nature Cell Biology. 2012 14: 1282–1294 https://doi.org/10.1038/ncb2628
- Distinct contribution of stem and progenitor cells to epidermal maintenance. Mascré G, Dekoninck S, Drogat B, Youssef KK, Brohée S, Sotiropoulou PA, Simons BD, Blanpain C. Nature. 2012 489, 257–262 https://doi.org/10.1038/nature11393
- A vascular niche and a VEGF–Nrp1 loop regulate the initiation and stemness of skin tumours. Beck B, Driessens G, Goossens G, Youssef KK, Loges S, Caauwe A, Kuchnio A, Sotiropoulou PA, Candi A, Mascre M, Haigh JJ, Carmeliet P, and Blanpain C. Nature. 2011 478, 399–403 https://doi.org/10.1038/nature10525
- Identifying the cellular origin of squamous skin tumors. Lapouge G*, Youssef KK*, Vokaer B, Achouri Y, Michaux C, Sotiropoulou PA, Blanpain C. PNAS. 2011 108 (18): 7431-7436 https://doi.org/10.1073/pnas.1012720108
- Bcl-2 and accelerated DNA repair mediates resistance of hair follicle bulge stem cells to DNA-damage-induced cell death. Sotiropoulou PA, Candi A, Mascré G, De Clercq S, Youssef KK, Lapouge G, Dahl E, Semeraro C, Denecker G, Marine JC and Blanpain C. Nature Cell Biology. 2010 12: 572–582 ; Highlighted in Nature Reviews Molecular and Cellular Biology. https://doi.org/10.1038/ncb2059
- Identification of the cell lineage at the origin of basal cell carcinoma. Youssef KK*, Van Keymeulen A*, Lapouge G*, Beck B, Achouri Y, Michaux C, Sotiropoulou P and Blanpain C. Nat Cell Biol. 2010 12, 299–305 ; Cover paper and highlighted by a preview in Cell Stem cell. https://doi.org/10.1038/ncb2031
Khalil Kass Youssef