Targeting CAG repeat RNAs reduces Huntington's disease phenotype independently of huntingtin levels.

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Targeting CAG repeat RNAs reduces Huntington’s disease phenotype independently of huntingtin levels.

Targeting CAG repeat RNAs reduces Huntington’s disease phenotype independently of huntingtin levels.

Rué L, Bañez-Coronel M, Creus-Muncunill J, Giralt A, Alcalá-Vida R, Mentxaka G, Kagerbauer B, Zomeño-Abellán MT, Aranda Z, Venturi V, Pérez-Navarro E, Estivill X, Martí E.

Revista J Clin Invest.

Año de publicación 2016

Volumen: Páginas(inicio-fin) 126(11): 4319-4330

DOI https://doi.org/10.1172/jci83185

Grupos de Investigación

→ Línea emergente: Arquitectura del genoma en el sistema nervioso

Targeting CAG repeat RNAs reduces Huntington’s disease phenotype independently of huntingtin levels.

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