Personal
Berta López Sánchez-Laorden
Group leader
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Cell Plasticity in Development and Disease
https://in.umh-csic.es/group3902
- Mecanismos Reguladores de Plasticidad de Melanoma y Metástasis Cerebrales
- Impact of oligodendroglia on melanoma brain metastases (OLIGO)
- Caracterización de nuevas estrategias terapéuticas para metástasis cerebrales de melanoma
- To identify and target the key events in the alterations of immunogenicity and response to immunotherapies in metastatic melanomas resistant to targeted therapies
- Becas Leonardo BBVA 2025
- Explotando la reprogramación del microambiental tumoral como estrategia terapéutica en metástasis cerebrales
- A hormetic transcriptional program coregulates invasion, proliferation and dormancy to define metastatic potential. Jiménez-Castaño, R., Narwade, N., Moreno-Bueno, G., Sánchez-Laorden, B., Galcerán, J., Youssef, K.K. and Nieto, M.A. Nature Communications. 2026 17: 3425 https://doi.org/10.1038/s41467-026-70242-4
- Cx43 enhances response to BRAF/MEK inhibitors by reducing DNA repair capacity. Adrián Varela-Vázquez, Amanda Guitián-Caamaño, Paula Carpintero-Fernández, Alexander Carneiro-Figueira, Vanesa Álvarez, Marta Varela-Eirín, Teresa Calleja-Chuclá, Susana B. Bravo-López, Anxo Vidal, Juan Sendón-Lago, Marina Rodriguez-Candela Mateos, José R. Caeiro, Victoria Sanz-Moreno, Trond Aasen, Miguel G. Blanco, Guadalupe Sabio, María Quindós, Carmen Rivas, David Santamaría, Carlos Fernandez-Lozano, Eduardo Fonseca, Pablo Huertas, Berta Sánchez-Laorden, Constance Alabert & María D. Mayán. Nature Communications. 2025 16: article num. 6168 https://doi.org/10.1038/s41467-025-60971-3
- Melanoma innervation, noradrenaline and cancer progression in zebrafish xenograft model. Francesca Lorenzini, Johanna Marines, Julien Le Friec, Nam Do Khoa, Maria Angela Nieto, Berta Sanchez-Laorden, Maria Caterina Mione, Laura Fontenille & Karima Kissa. Cell Death Discov. 2025 11- Article num. 260 (2025) https://doi.org/10.1038/s41420-025-02523-8
- Microglial reprogramming enhances antitumor immunity and immunotherapy response in melanoma brain metastases. Rodriguez-Baena FJ, Marquez-Galera A, Ballesteros Martínez P, Castillo A, Diaz E, Moreno-Bueno G, Lopez-Atalaya JP and Sanchez-Laorden B. Cancer Cell. 2025 43(3), 1–15 https://doi.org/10.1016/j.ccell.2025.01.008
- Protocol for generation, quantification, and phenotyping of brain metastases in preclinical mouse models. Francisco Javier Rodriguez-Baena, Berta Sanchez-Laorden. Protocol. 2025 6(3): art. number 103978 https://doi.org/10.1016/j.xpro.2025.103978
- Schwann cells in regeneration and cancer: an epithelial–mesenchymal transition perspective. Francisco Gracia, Berta Sanchez-Laorden and Jose A. Gomez-Sanchez. Open Biology. 2025 15(3) - Review Article https://doi.org/10.1098/rsob.240337
- Metabolic rewiring induced by ranolazine improves melanoma responses to targeted therapy and immunotherapy. Redondo-Muñoz M, Rodriguez-Baena FJ, Aldaz P, Caballé-Mestres A, Moncho-Amor V, Otaegi-Ugartemendia M, Carrasco-Garcia E, Olias-Arjona A, Lasheras-Otero I, Santamaria E, Bocanegra A, Chocarro L, Grier A, Dzieciatkowska M, Bigas C, Martin J, Urdiroz-Urricelqui U, Marzo F, Santamaria E, Kochan G, Escors D, Larrayoz IM, Heyn H, D’Alessandro A, Stephan-Otto Attolini C, Matheu A, Wellbrock C, Aznar Benitah S, Sanchez-Laorden B & Arozarena I. Nature Metabolism. 2023 5 (9), pp. 1544 - 1562 https://doi.org/10.1038/s42255-023-00861-4
- Microenvironmental Snail1-induced immunosuppression promotes melanoma growth. Arumi-Planas M, Rodriguez-Baena FJ, Cabello-Torres F, Gracia F, Lopez-Blau C, Nieto MA, Sanchez-Laorden B. Oncogene 2023 42 (36), pp. 2659 - 2672 https://doi.org/10.1038/s41388-023-02793-5
- Neuronal Cannabinoid CB1 Receptors Suppress the Growth of Melanoma Brain Metastases by Inhibiting Glutamatergic Signalling. Costas-Insua, C.; Seijo-Vila, M.; Blázquez, C.; Blasco-Benito, S.; Rodríguez-Baena, F.J.; Marsicano, G.; Pérez-Gómez, E.; Sánchez, C.; Sánchez-Laorden, B.; Guzmán, M. Cancers . 2023 15: 2439 https://doi.org/10.3390/cancers15092439
- Antifibrotic drugs as therapeutic tools in resistant melanoma. Sanchez-Laorden B, Nieto MA. EMBO Mol Med. 2022 14(3):e15449 - Editorial https://doi.org/10.15252/emmm.202115449
- Functional interplay between secreted ligands and receptors in melanoma Herraiz C, Jiménez-Cervantes C, Sánchez-Laorden B, García-Borrón JC Semin Cell Dev Biol 2018 78:73 https://doi.org/10.1016/j.semcdb.2017.06.021
Berta López Sánchez-Laorden