Personal
Francisco José Taberner Sanchís
Group leader
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Wiring and Function of Somatosensory Circuits
https://in.umh-csic.es/group3878
- Functional and Cellular Characterization of Spinal Cord Circuits Involved in Chronic
- Determinación del papel de las células de Schwann nociceptivas en la neuropatía periférica inducida por quimioterapia
- Estudio de los mecanismos que regulan la distribución del canal mechanosensible PIEZO2 en las neuronas sensoriales y sus implicaciones fisiológicas
- Implementación de la captura de circuitos medulares mediante sistema de captura pRAM entregada por inyección intraespinal de AAVs
- Contribution of mechanoreceptors to spinal cord injury–induced mechanical allodynia. Sliwinski, C; Heutehaus, L; Taberner, Francisco J.; Weiss, L; Kampanis, V; Tolou-Dabbaghian, B; Cheng, X; Motsch, M; Heppenstall, P; Kuner, R; Franz, S; Lechner, S; Weidner, N; Puttagunta, R PAIN 2024 165(6): 1336-1347 https://doi.org/10.1097/j.pain.0000000000003139
- OCaR1 endows exocytic vesicles with autoregulatory competence by preventing uncontrolled Ca2+ release, exocytosis, and pancreatic tissue damage. Tsvilovskyy , Ottenheijm , Kriebs , Schütz, Diakopoulos, Jha , Bildl, Wirth, Böck , Jaślan, Ferro , FJ Taberner ,Kalinina , Hildebrand , Wissenbach, Weissgerber , Vogt, Eberhagen, Mannebach, Berlin, Kuryshev, Schumacher ,Philippaert, Camacho-Londoño , Mathar, Dieterich, Klugbauer, Biel , Wahl-Schott , Lipp , Flockerzi , Zischka, Algül, Lechner , Lesina, Grimm, Fakler, Schulte , Muallem , Freichel J Clin Invest. 2024 134(7): e169428 https://doi.org/10.1172/JCI169428
- The ion channel TRPM8 is a direct target of the immunosuppressant rapamycin in primary sensory neurons. Arcas JM, Oudaha K, González A, Fernández-Trillo J, Peralta FC, Castro-Marsal J, Poyraz S, Tabener F, Sala S, de la Peña E, gomis A, Viana F. British Journal of Pharmacology. 2024 First published: 13 May 2024 https://doi.org/10.1111/bph.16402
- Role of TMEM100 in mechanically insensitive nociceptor un-silencing. Timo A. Nees, Na Wang, Pavel Adamek, Nadja Zeitzschel, Clement Verkest, Carmen La Porta, Irina Schaefer, Julie Virnich, Selin Balkaya, Vincenzo Prato, Chiara Morelli, Valerie Begay, Young Jae Lee, Anke Tappe-Theodor, Gary R. Lewin, Paul A. Heppenstall, Francisco J. Taberner & Stefan G. Lechner Nat Commun. 2023 14, Art. 1899 https://doi.org/10.1038/s41467-023-37602-w
- Intrinsically disordered intracellular domains control key features of the mechanically-gated ion channel PIEZO2 Verkest, C., Schaefer, I., Nees, T.A., Wang, N., Jegelka, J.M., Taberner, F.J., Lechner, S.G. Nature Communications 2022 13(1): art 1365 http://doi.org/10.1038/s41467-022-28974-6
- Neuropathic pain caused by miswiring and abnormal end organ targeting. Gangadharan V, Zheng H, Taberner FJ, Landry J, Nees TA, Pistolic J, Agarwal N, Männich D, Benes V, Helmstaedter M, Ommer B, Lechner SG, Kuner T, Kuner R. Nature. 2022 606 (7912): 137-145 https://doi.org/10.1038/s41586-022-04777-z
- Identification of a population of peripheral sensory neurons that regulates blood pressure Morelli C,Castaldi L, Brown SJ, Streich LL, Websdale A, Taberner FJ, Cerreti B, Barenghi A, Blum KM, Sawitzke J, Frank T, Steffens LK, Doleschall B, Serrao J, Ferrarini D, Lechner SG, Prevedel R, Heppenstall PA. Cell Reports 2021 35(9) https://doi.org/10.1016/j.celrep.2021.109191
- USH2A is a Meissner’s corpuscle protein necessary for normal vibration sensing in mice and humans Schwaller F , Bégay V, García-García G, Taberner FJ, Moshourab R, McDonald B, Docter T, Kühnemund J, Ojeda-Alonso J, Paricio-Montesinos R, Lechner SG, Poulet JFA, Millan JM, Lewin GR Nat Neurosci 2021 24(1):74 https://doi.org/10.1038/s41593-020-00751-y
- SUMOylation of Enzymes and Ion Channels in Sensory Neurons Protects against Metabolic Dysfunction, Neuropathy, and Sensory Loss in Diabetes Agarwal N , Taberner FJ, Rangel Rojas D, Moroni M, Omberbasic D, Njoo C, Andrieux A, Gupta P, Bali KK, Herpel E, Faghihi F, Fleming T, Dejean A, Lechner SG, Nawroth PP, Lewin GR, Kuner R. Neuron 2020 107(6):1141 https://doi.org/10.1016/j.neuron.2020.06.037
- Structure-guided examination of the mechanogating mechanism of PIEZO2 Taberner FJ,Prato V, Schaefer I, Schrenk-Siemens K, Heppenstall PA, Lechner SG Proc Natl Acad Sci USA 2019 116(28):14260 https://doi.org/10.1073/pnas.1905985116
- Hyaluronan modulates TRPV1 channel opening, reducing peripheral nociceptor activity and pain Caires R, Luis E, Taberner FJ, Fernandez-Ballester G, Ferrer-Montiel A, Balazs EA, Gomis A, Belmonte C, De la Peña E Nat Commun 2015 6:8095 https://doi.org/10.1038/ncomms9095
Francisco José Taberner Sanchís