Personal
Francisco Luis Sala Merchán
Staff Scientist
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Translational neuropsychopharmacology of neurological and psychiatric diseases
https://in.umh-csic.es/group3901
- Natural Polyhydroxy Flavonoids, Curcuminoids, and Synthetic Curcumin Analogs as a7 nAChRs Positive Allosteric Modulators Ximenis M, Mulet J, Sala S, Sala F, Criado M, González-Muñiz R, Pérez de Vega MJ Int J Mol Sci 2021 22(2):973 https://doi.org/10.3390/ijms22020973
- Biomarkers in Psychiatry: Concept, Definition, Types and Relevance to the Clinical Reality García-Gutiérrez MS, Navarrete F, Sala F, Gasparyan A, Austrich-Olivares A, Manzanares J Front Psychiatry 2020 11:432 https://doi.org/10.3389/fpsyt.2020.00432
- Cannabidiol: A Potential New Alternative for the Treatment of Anxiety, Depression, and Psychotic Disorders García-Gutiérrez MS, Navarrete F, Gasparyan A, Austrich-Olivares A, Sala F, Manzanares J Biomolecules 2020 10(11):1575 https://doi.org/10.3390/biom10111575
- 1-(2 ‘,5 ‘-Dihydroxyphenyl)-3-(2-fluoro-4-hydroxyphenyl)-1-propanone (RGM079): A Positive Allosteric Modulator of alpha 7 Nicotinic Receptors with Analgesic and Neuroprotective Activity Perez de Vega MJ, Fernandez-Mendivil C, de la Torre-Martinez R, Gonzalez-Rodriguez S, Mullet J, Sala F, Sala S, Criado M, Moreno-Fernandez S, Miguel M, Fernandez-Carvajal A, Ferrer-Montiel A, Lopez MG, Gonzalez-Muniz R ACS Chem Neurosci 2019 10(8):3900 https://doi.org/10.1021/acschemneuro.9b00364
- Amino acid and peptide prodrugs of diphenylpropanones positive allosteric modulators of alpha 7 nicotinic receptors with analgesic activity Balsera B, Mulet J, Sala S, Sala F, de la Torre-Martinez R, Gonzalez-Rodriguez S, Plata A, Naesens L, Fernandez-Carvajal A, Ferrer-Montiel A, Criado M, Perez de Vega MJ, Gonzalez-Muniz R Eur J Med Chem 2018 143:157 https://doi.org/10.1016/j.ejmech.2017.https://doi.org/10.083
- 1,3-diphenylpropan-1-ones as allosteric modulators of alpha 7 nACh receptors with analgesic and antioxidant properties Criado M, Balsera B, Mulet J, Sala S, Sala F, de la Torre-Martinez R, Fernandez-Carvajal A, Ferrer-Montiel A, Moreno-Fernandez S, Miguel M, Perez de Vega MJ, Gonzalez-Muñiz R Future Med Chem 2016 8(7):731 https://doi.org/10.4155/fmc-2015-0001
- N-Benzylpiperidine Derivatives as alpha 7 Nicotinic Receptor Antagonists Criado M, Mulet J, Sala F, Sala S, Colmena I, Gandia L, Bautista-Aguilera OM, Samadi A, Chioua M, Marco-Contelles J ACS Chem Neurosci 2016 7(8):1157 https://doi.org/10.1021/acschemneuro.6b00122
- Chalcones as positive allosteric modulators of alpha-7 nicotinic acetylcholine receptors: A new target for a privileged structure Balsera B, Mulet J, Fernandez-Carvajal A, Torre-Martinez Rde L, Ferrer-Montiel A, Hernandez-Jimenez JG, Estevez-Her, Borges R, Freitas AE, Lopez MG, Garcia-Lopez MT, Gonzalez-Muñiz R, Perez de Vega MJ, Valor LM, Svobodova L, Sala S, Sala F, Criado M Eur J Med Chem 2014 86:724 https://doi.org/10.1016/j.ejmech.2014.09.039
- Effect of triazine derivatives on neuronal nicotinic receptors Vazquez-Romero A, Criado M, Messeguer A, Vidal-Mosquera M, Mulet J, Sala F, Sala S ACS Chem Neurosci 2014 5(8):683 https://doi.org/10.1021/cn5000748
- Expression and functional properties of a7 acetylcholine nicotinic receptors are modified in the presence of other receptor subunits Criado M, Valor LM, Mulet J, Gerber S, Sala S, Sala F J Neurochem 2012 123(4):504 https://doi.org/10.1111/j.1471-4159.2012.07931.x
- A small cytoplasmic region adjacent to the fourth transmembrane segment of the alpha 7 nicotinic receptor is essential for its biogenesis Criado M, Mulet J, Gerber S, Sala S, Sala F FEBS Lett 2011 585(15):2477 https://doi.org/10.1016/j.febslet.2011.06.028
- Mutants of beta-strand beta 3 and the loop B in the interface between alpha 7 subunits of a homomeric acetylcholine receptor show functional and pharmacological alterations Criado M, Mulet J, Gerber S, Sala S, Sala F J Neurochem 2011 118(6):968 https://doi.org/10.1111/j.1471-4159.2011.07381.x
- Substitutions of amino acids in the pore domain of homomeric alpha 7 nicotinic receptors for analogous residues present in heteromeric receptors modify gating, rectification and binding properties Criado M, Svobodova L, Mulet J, Sala F, Sala S J Neurochem 2011 119(1):40 https://doi.org/10.1111/j.1471-4159.2011.07398.x
- P2X4 Activation Modulates Volume-sensitive Outwardly Rectifying Chloride Channels in Rat Hepatoma Cells Varela D, Penna A, Simon F, Eguiguren AL, Leiva-Salcedo E, Cerda O, Sala F, Stutzin A J Biol Chem 2010 285(10):7566 https://doi.org/10.1074/jbc.M109.063693
- Role of loop 9 on the function of neuronal nicotinic receptors Criado M, Castillo M, Mulet J, Sala F, Sala S BBA-Biomembranes 2010 1798(3):654 https://doi.org/10.1016/j.bbamem.2009.12.013
- Role of the extracellular transmembrane domain interface in gating and pharmacology of a heteromeric neuronal nicotinic receptor Aldea M, Castillo M, Mulet J, Sala S, Criado M, Sala F J Neurochem 2010 113(4):1036 https://doi.org/10.1111/j.1471-4159.2010.06665.x
- The loop between beta-strands beta 2 and beta 3 and its interaction with the N-terminal alpha-helix is essential for biogenesis of alpha 7 nicotinic receptors Criado M, Mulet J, Castillo M, Gerber S, Sala S, Sala F J Neurochem 2010 112(1):103 https://doi.org/10.1111/j.1471-4159.2009.06439.x
Francisco Luis Sala Merchán