Personal
Ana Gomis García
Group leader
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Sensory transduction and nociception
https://in.umh-csic.es/group3906
- Mecanismos Celulares y Moleculares del Dolor Inducido por Quimioterapia: Preparando el Camino para la Prevención y el Tratamiento
- PROMETEO: “CHEMOTHERAPY-INDUCED CHRONIC NEUROPATHY: PATHOPHYSIOLOGY, PROGNOSTIC BIOMARKERS AND PREVENTIVE THERAPIES”
- Piezo2 mediates mechanical sensitivity and injury-induced hypersensitivity in MrgprD-expressing nociceptors. Fernández-Trillo, J., Villaro-Capellán, M., de la Peña, E., Viana, F. & Gomis, A. PAIN. 2026 167(6):1404-1416 ; Editor’s Choice article https://doi.org/10.1097/j.pain.0000000000003954
- Validation of TRPA1 and TRPV1 antibodies for expression detection in mammalian cells and tissues. De las Casas Manuela, Hernández-Ortego Pablo, Torres-Montero Remedios, de la Peña Elvira, Gomis Ana, Viana Félix, Fernández-Trillo J. Journal of Neurochemistry. 2026 170: e70444 https://onlinelibrary.wiley.com/doi/full/10.1111/jnc.70444
- Proper Frequency of Perinatal Retinal Waves Is Essential for the Precise Wiring of Visual Axons in Nonimage-Forming Nuclei. Negueruela S, Morenilla-Palao C, Herrera M, Coca Y, Florez-Paz D, López-Cascales MT, Gomis A, Herrera E*. J Neurosci. 2024 44 (40): e1408232024 https://doi.org/10.1523/JNEUROSCI.1408-23.2024
- The ion channel TRPM8 is a direct target of the immunosuppressant rapamycin in primary sensory neurons. Arcas JM, Oudaha K, González A, Fernández-Trillo J, Peralta FC, Castro-Marsal J, Poyraz S, Tabener F, Sala S, de la Peña E, gomis A, Viana F. British Journal of Pharmacology. 2024 First published: 13 May 2024 https://doi.org/10.1111/bph.16402
- TRPA1 modulation by Sigma-1 receptor prevents oxaliplatin-induced painful peripheral neuropathy Marcotti, A., Fernández-Trillo, J., González, A., Vizcaíno-Escoto, M., Ros-Arlanzón, P., Romero, L., Vela, J. M., Gomis, A., Viana, F., & de la Peña, E Brain 2023 146 (2): 475-491 https://doi.org/10.1093/brain/awac273
- Expression of the cold thermoreceptor TRPM8 in rodent brain thermoregulatory circuits Ordás P, Hernández-Ortego P, Vara H, Fernández-Peña C, Reimúndez A, Morenilla-Palao C, Guadaño-Ferraz A, Gomis A, Hoon M, Viana F, Señarís R J Comp Neurol 2021 529(1):234 https://doi.org/10.1002/cne.24694
- Piezo2 mediates low-threshold mechanically-evoked pain in the cornea Fernández-Trillo J, Florez-Paz D, Iñigo-Portugués A, González-González O, Del Campo AG, González A, Viana F, Belmonte C, Gomis A J Neurosci 2020 40(47):8976 https://doi.org/10.1523/JNEUROSCI.0247-20.2020
- The immunosuppressant macrolide tacrolimus activates cold-sensing TRPM8 channels Miguel Arcas J, Gonzalez A, Gers-Barlag K, Gonzalez-Gonzalez O, Bech F, Demirkhanyan L, Zakharian E, Belmonte C, Gomis A, Viana F Journal of Neuroscience 2019 39(6):949 https://doi.org/10.1523/JNEUROSCI.1726-18.2018
- Joint nociceptor nerve activity and pain in an animal model of acute gout and its modulation by intra-articular hyaluronan Marcotti A, Miralles A, Dominguez E, Pascual E, Gomis A, Belmonte C, de la Pena E Pain 2018 159(4):739 https://doi.org/10.1097/j.pain.0000000000001137
- A critical role for Piezo2 channels in the mechanotransduction of mouse proprioceptive neurons Florez-Paz D, Bali KK, Kuner R, Gomis A Sci Rep 2016 6:25923 https://doi.org/10.1038/srep25923
- TRPV1 channel modulation by hyaluronan reduces pain de la Peña E, Gomis A, Ferrer-Montiel A, Belmonte C Channels (Austin) 2016 10(2):81 https://doi.org/10.1080/19336950.2015.1109300
- Hyaluronan modulates TRPV1 channel opening, reducing peripheral nociceptor activity and pain Caires R, Luis E, Taberner FJ, Fernandez-Ballester G, Ferrer-Montiel A, Balazs EA, Gomis A, Belmonte C, De la Peña E Nat Commun 2015 6:8095 https://doi.org/10.1038/ncomms9095
- G protein-coupled receptor signalling potentiates the osmo-mechanical activation of TRPC5 channels Jemal I, Soriano S, Conte AL, Morenilla C, Gomis A Pflugers Arch 2014 466(8):1635 https://doi.org/10.1007/s00424-013-1392-z
- Blockade of nociceptive sensory afferent activity of the rat knee joint by the bradykinin B2 receptor antagonist fasitibant Gomis A, Meini S, Miralles A, Valenti C, Giuliani S, Belmonte C, Maggi CA Osteoarthr Cartilage 2013 21(9):1346 https://doi.org/10.1016/j.joca.2013.03.013
- Monoacylglycerols Activate TRPV1-A Link between Phospholipase C and TRPV1 Zygmunt PM, Ermund A, Movahed P, Andersson DA, Simonsen C, Jönsson BA, Blomgren A, Birnir B, Bevan S, Eschalier A, Mallet C, Gomis A, Högestätt ED PLoS One 2013 8(12):e81618 https://doi.org/10.1371/journal.pone.0081618
- Membrane-tethered peptides patterned after the TRP domain (TRPducins) selectively inhibit TRPV1 channel activity Valente P, Fernandez-Carvajal A, Camprubi-Robles M, Gomis A, Quirce S, Viana F, Fernandez-Ballester G, Gonzalez-Ros JM, Belmonte C, Planells-Cases R, Ferrer-Montiel A FASEB J 2011 25(5):1628 https://doi.org/10.1096/fj.10-174433
Ana Gomis García