Personal
Elvira De la Peña García
Group leader
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Sensory transduction and nociception
https://in.umh-csic.es/group3906
- Light-induced analgesia provides a drug-free optical method for pain relief via activation of TRAAK k+ channels. Marion Bied, Arnaud Landra-Willm, Anne Amandine Chassot, Edward Francisco Mendez-Otalvaro, Benjamin Sueur, Kilian Roßmann, Elvira de la Peña, Pascal Fossat, Stephen J. Tucker, Jacques Noël, Wojciech Kopec, Felix Viana, Johannes Broichhagen, Eric Boué-Grabot & Guillaume Sandoz. Nat Commun. 2026 17, 620 https://doi.org/10.1038/s41467-025-67819-w
- Piezo2 mediates mechanical sensitivity and injury-induced hypersensitivity in MrgprD-expressing nociceptors. Fernández-Trillo, J., Villaro-Capellán, M., de la Peña, E., Viana, F. & Gomis, A. PAIN. 2026 167(6):1404-1416 ; Editor’s Choice article https://doi.org/10.1097/j.pain.0000000000003954
- Validation of TRPA1 and TRPV1 antibodies for expression detection in mammalian cells and tissues. De las Casas Manuela, Hernández-Ortego Pablo, Torres-Montero Remedios, de la Peña Elvira, Gomis Ana, Viana Félix, Fernández-Trillo J. Journal of Neurochemistry. 2026 170: e70444 https://onlinelibrary.wiley.com/doi/full/10.1111/jnc.70444
- The ion channel TRPM8 is a direct target of the immunosuppressant rapamycin in primary sensory neurons. Arcas JM, Oudaha K, González A, Fernández-Trillo J, Peralta FC, Castro-Marsal J, Poyraz S, Tabener F, Sala S, de la Peña E, gomis A, Viana F. British Journal of Pharmacology. 2024 First published: 13 May 2024 https://doi.org/10.1111/bph.16402
- TRPA1 modulation by Sigma-1 receptor prevents oxaliplatin-induced painful peripheral neuropathy Marcotti, A., Fernández-Trillo, J., González, A., Vizcaíno-Escoto, M., Ros-Arlanzón, P., Romero, L., Vela, J. M., Gomis, A., Viana, F., & de la Peña, E Brain 2023 146 (2): 475-491 https://doi.org/10.1093/brain/awac273
- Validation of Six Commercial Antibodies for the Detection of Heterologous and Endogenous TRPM8 Ion Channel Expression. Hernández-Ortego, P., Torres-Montero, R., de la Peña, E., Viana, F., Fernández-Trillo, J. Int J Mol Sci. 2022 23(24): 16164 https://doi.org/10.3390/ijms232416164
- Joint nociceptor nerve activity and pain in an animal model of acute gout and its modulation by intra-articular hyaluronan Marcotti A, Miralles A, Dominguez E, Pascual E, Gomis A, Belmonte C, de la Pena E Pain 2018 159(4):739 https://doi.org/10.1097/j.pain.0000000000001137
- Hyaluronan modulates TRPV1 channel opening, reducing peripheral nociceptor activity and pain Caires R, Luis E, Taberner FJ, Fernandez-Ballester G, Ferrer-Montiel A, Balazs EA, Gomis A, Belmonte C, De la Peña E Nat Commun 2015 6:8095 https://doi.org/10.1038/ncomms9095
- The Influence of Cold Temperature on Cellular Excitability of Hippocampal Networks de la Peña E, Mälkiä A, Vara H, Caires R, Ballesta JJ, Belmonte C, Viana F PLoS ONE 2012 7(12):e52475 https://doi.org/10.1371/journal.pone.0052475
Elvira De la Peña García