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Fase I (2012-2015)
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INICIO Fase I >>



Ateca-Cabarga JC, Cosa A, Pallares V, Lopez-Atalaya JP, Barco A, Canals S, Moratal D (2015). Brain size regulations by cbp haploinsufficiency evaluated by in vivo MRI based volumetry. Sci Reports, in press.

Scandaglia M, Benito E, Morenilla-Palao C, Fiorenza F, del Blanco B, Coca Y, Herrera E, Barco A. Fine-tuned SRF activity controls asymmetrical neuronal outgrowth: implications for cortical migration, neural tissue lamination and circuit assembly. Sci Reports, in press.

Murillo M, Ruiz-Reig N, Herrera M, Fairén A and Herrera E (2015) Zic2 Controls the Migration of Specific Neuronal Populations in the Developing Forebrain. The journal of Neuroscience 35(32):11266-11280.

Barco A, Brambilla R, Rosenblum K (2015). Editorial. Neurobiol Learn Mem 124:1-2. Special Issue Guest Editor.

Fiorenza A, Lopez-Atalaya JP, Rovira V, Geijo-Barrientos E, Barco A. Blocking miRNA biogenesis in adult forebrain neurons enhances seizure susceptibility, fear memory and food intake by increasing neuronal responsiveness. Cereb Cortex 2015 Jan 16. pii: bhu332. [Epub ahead of print]

Del Blanco B, Medrano A, Barco A (2015). Neuroepigenética, en la interfase entre genoma y cerebro. SEBBM Mar 2015 183: 21-26.

Lopez-Atalaya JP, Valor LM, Barco A (2014). Epigenetic factors in intellectual disability: the rubinstein-taybi syndrome as a paradigm of neurodevelopmental disorder with epigenetic origin. Prog Mol Biol Transl Sci (2014) 128:139-76.

Benito E and Barco A (2015). The Neuronal Activity-Driven Transcriptome. Mol Neurobiol. 289(47):32914-25.


Erskine and Herrera (2014). Connecting the eye to the brain. ASN Neuro. In press.

Lopez-Atalaya J, Valor LM and Barco A (2014). Epigenetic factors in intellectual disability: The Rubinstein–Taybi syndrome as a paradigm of neurodevelopmental disorder with epigenetic origin. Epigenetics and Neuroplasticity - Evidence and Debate, PMBTS Volume 128 (Elsevier, 2014) In press.

Ma TC, Barco A, Ratan RR and Willis DE. (2014). cAMP Responsive Element Binding Protein (CREB) and cAMP Co-regulate Activator Protein 1 (AP1)-Dependent Regeneration-Associated Gene Expression and Neurite Growth. J Biol Chem, Oct 8 [Epub ahead of print]



Lopez-Atalaya J, and Barco A (2014). Can changes in histone acetylation contribute to memory formation? Trends Genet, Sep 27 [Epub ahead of print].

Balsera B, Mulet J, Fernández-Carvajal A, Torre-Martínez Rde L, Ferrer-Montiel A, Hernández-Jiménez JG, Estévez-Herrera J, Borges R, Freitas AE, López MG, García-López MT, González-Muñiz R, Pérez de Vega MJ, Valor LM, Svobodová L, Sala S, Sala F, Criado M (2014). Chalcones as positive allosteric modulators of α7 nicotinic acetylcholine receptors: A new target for a privileged structure. Eur J Med Chem. Oct 30;86:724-39.

Alcaraz-Iborra M, Carvajal F, Lerma-Cabrera JM, Valor LM, Cubero I (2014). Binge-like consumption of caloric and non-caloric palatable substances in ad libitum-fed C57BL/6J mice: pharmacological and molecular evidence of orexin involvement. Behav Brain Res. Oct 1;272:93-9.

Ito S, Magalska A, Alcaraz-Iborra M, Lopez-Atalaya JP, Rovira V, Contreras-Moreira B, Lipinski M, Olivares R, Martinez-Hernandez J, Ruszczycki B, Lujan R, Geijo-Barrientos E, Wilczynski GM and Barco A (2014). Loss of neuronal 3D chromatin organization causes transcriptional and behavioural deficits related to serotonergic dysfunction. Nat Commun. 2014 Jul 18;5:4450.

Valor LM (2014). Transcription, Epigenetics and Ameliorative Strategies in Huntington's Disease: a Genome-Wide Perspective. Mol Neurobiol. 2014 May 1 [Epub ahead of print].

Yildirim F, Ji S, Kronenberg G, Barco A, Olivares R, Benito E, Dirnagl U, Gertz K, Endres M, Harms C and Meisel A (2014). Histone acetylation and CREB binding protein are required for neuronal resistance against ischemic injury. Plos ONE 9(4).

Valor LM and Guiretti D (2014). What's wrong with epigenetics in Huntington's disease? Neuropharmacology 80: 103-14.

Barco A (2014). Neuroepigenetic disorders: Progress, promises and challenges. Neuropharmacology 80: 1-2.


Escalante E, Murillo B, Morenilla-Palao C, Klar A and Herrera E* (2013). Zic2-dependent axon midline avoidance controls the formation of major ipsilateral tracts in the CNS. Neuron. 80(6), 1392–1406.

Benjumeda I, Escalante A, Law C, Morales D, Chauvin G, Muca G, Coca Y, López-Bendito G, Kania A, Martínez-Otero L and Herrera E* (2013). Uncoupling of EphA/ephrinA signaling and spontaneous activity in neural circuit wiring. The Journal of Neuroscience 33(46):18208-18218. Cover caption.



Herrera E* and Erskine L (2013). Visual system Development in vertebrates. Encyclopedia of Life Sciences (eLS) John Wiley & Sons, Ltd.

Sanchez-Arrones L, Nieto-López F, Sánchez-Camacho C, Carreres MI, Herrera E, Okada A, Bovolenta P*. (2013). Shh/Boc signaling is required for sustained generation of ipsilateral-projecting ganglion cells in the mouse retina. The Journal of Neuroscience 33(20):8596-607.

Parkel S, Lopez-Atalaya JP and Barco A (2013). Histone H3 methylation in cognition and intellectual disability disorders. Learn Mem 20:570-79.

Lopez-Atalaya JP, Ito S, Valor LM, Benito E and Barco A (2013). Genomic targets, and histone acetylation and gene expression profiling of neural HDAC inhibition. Nucleic Acids Res 41(17):8072-84.

Valor LM*, Guiretti D*, Lopez-Atalaya JP* and Barco A (2013). Genomic landscape of transcriptional and epigenetic dysregulation in early-onset polyglutamine disease. J Neurosci 33(25):10471-82.*: Equal contributors.

Valor LM, Viosca J, Lopez-Atalaya JP and Barco A (2013). Lysine acetyltransferases CBP and p300 as therapeutic targets in cognitive and neurodegenerative disorders. Curr Pharm Des 19(28):5051-64.


Agnes Gruart, Eva Benito, Jose M. Delgado-Garcia and Angel Barco (2012). Enhanced cAMP Response Element-Binding Protein Activity Increases Neuronal Excitability, Hippocampal Long-Term Potentiation, and Classical Eyeblink Conditioning in Alert Behaving Mice. J Neurosci 32(48): 17431-41.pubmed

Criado M, Valor LM, Mulet J, Gerber S, Sala S and Sala F (2012).Expression and functional properties of a7 acetylcholine nicotinic receptors are modifies in the presence of other receptor subunits. J. Neurochem. 123(4):504-14.

Lopez-Atalaya JP*, Gervasini C*, Mottadelli F, Spina S, Piccione M, Scarano G, Selicorni A, Barco Aº, Larizza Lº (2012) Histone acetylation deficits in lymphoblastoid cell lines from Rubinstein-Taybi syndrome patients. J Med Genet 66-74.*,º: Equal contributors.

Valor LM and Barco A (2012) Hippocampal gene profiling: Toward a systems biology of the hippocampus. Hippocampus 22(5):929-4.