Research Highlights: Archive

1. Alegre-Cortés, J., Sáez, M., Montanari, R., Reig, R.Medium spiny neurons activity reveals the discrete segregation of mouse dorsal striatum (2021) Life, 10, art. no. e60580, pp. 1-41. OPEN ACCESS: All Open Access, Gold, Green
2. Aleixandre-Carrera, F., Engelmayer, N., Ares-Suárez, D., Acosta, M.C., Belmonte, C., Gallar, J., Meseguer, V., Binshtok, A.M. Optical assessment of nociceptive TRP channel function at the peripheral nerve terminal. (2021) International Journal of Molecular Sciences, 22 (2), art. no. 481, pp. 1-20. OPEN ACCESS: All Open Access, Gold
3. Álvarez-Vergara MI; Rosales-Nieves AE; March-Diaz R; Rodriguez-Perinan G; Lara-Ureña N; Ortega-de San Luis C; Sánchez-García MA; Martín-Bornez M; Gómez-Gálvez P; Vicente-Munuera P; Fernández-Gómez B; Marchena MA; Bullones-Bolaños AS; Dávila JC; González-Martínez R; Trillo-Contreras JL; Sánchez-Hidalgo AC; del Toro R; Scholl FG; Herrera E; Trepel M; Körbelin J; Escudero LM; Villadiego J; Echevarria M; de Castro F; Gutiérrez A; Rábano A; Vitorica J; Pascual A.Non-productive angiogenesis disassembles Aß plaque-associated blood vessels. (2021) Nature Communications 12(1):3098
4. Andreu-Cervera, A., Catala, M., Schneider-Maunoury, S.Cilia, ciliopathies and hedgehog-related forebrain developmental disorders. (2021) Neurobiology of Disease, 150, art. no. 105236. OPEN ACCESS: All Open Access, Gold
5. Barco, Angel ; María Gómez Vicentefranqueira; Sandra Blanco Benavente; Elena Gómez Díaz; Javier Martin; Marián Martínez Balbás; Jordi Pérez-Tur; Isidro Sánchez Garcia; Carles Suñé; Mario Vallejo. Chapter 5: Functional epigenetics and epitranscriptomics and their role in health and disease. (pp 103-121) in book “White Paper 3: Genome & Epigenetics” Ed: Consejo Superior de Investigaciones Científicas (CSIC) DOCUMENT TYPE: Book Chapter.
6. Bragg-Gonzalo, L.; De León Reyes, N.S.; Nieto, M.Genetic and activity dependent-mechanisms wiring the cortex: Two sides of the same coin. (2021) Seminars in Cell and Developmental Biology 118: 24-34. Review
7. Bueno, C., Martínez, S. Neurogenesis similarities in different human adult stem cells. (2021) Neural Regeneration Research, 16 (1), pp. 123-124. OPEN ACCESS: All Open Access, Gold, Green
8. Bueno, C.; Martínez-Morga, M.; García-Bernal, D.; Moraleda, J.M.; Martínez, S. 2021 Differentiation of human adult-derived stem cells towards a neural lineage involves a dedifferentiation event prior to differentiation to neural phenotypes.Scientific Reports 11(1): 12034.
9. Calpe-López, C., Gasparyan, A., Navarrete, F., Manzanares, J., Miñarro, J., Aguilar, M.A. Cannabidiol prevents priming- and stress-induced reinstatement of the conditioned place preference induced by cocaine in mice. (2021) Journal of Psychopharmacology.
10. Carmena, A. Non-muscle myosin II activation: adding a classical touch to ROCK. (2021) Small GTPases, 12 (3), pp. 161-166.
11. Cid E, Marquez-Galera A, Valero M, Gal B, Medeiros DC, Navarron CM, Ballesteros-Esteban L, Reig-Viader R, Morales AV, Fernandez-Lamo I, Gomez-Dominguez D, Sato M, Hayashi Y, Bayés À, Barco A, Lopez-Atalaya JP, de la Prida LM. “Sublayer- and cell-type-specific neurodegenerative transcriptional trajectories in hippocampal sclerosis". (2021) Cell Rep 35(10):109229. doi: 10.1016/j.celrep.2021.109229
12. Company V, Andreu-Cervera A, Madrigal MP, Andrés B, Almagro-García F, Chédotal A, López-Bendito G, Martinez S, Echevarría D, Moreno-Bravo JA and Puelles E."Netrin 1-Mediated Role of the Substantia Nigra Pars Compacta and Ventral Tegmental Area in the Guidance of the Medial Habenular Axons." (2021) Front. Cell Dev. Biol., 08 June 2021 | https://doi.org/10.3389/fcell.2021.682067
13. Conde-Dusman M.J, Partha N Dey, Óscar Elía-Zudaire, Luis G Rabaneda, Carmen García-Lira, Teddy Grand, Victor Briz, Eric R Velasco, Raül Andero, Sergio Niñerola, Angel Barco, Pierre Paoletti, John F Wesseling, Fabrizio Gardoni, Steven J Tavalin, Isabel Perez-Otaño."Control of protein synthesis and memory by GluN3A-NMDA receptors through inhibition of GIT1/mTORC1 assembly." (2021) eLife. Nov 17, 2021; 10:e71575 / DOI: 10.7554/eLife.71575
14. Cuchillo-Ibañez I, Lennol M, Escamilla S, Mata-Balaguer T, Valverde-Vozmediano L, Lopez-Font I, Ferrer I, Sáez-Valero J."The apolipoprotein receptor LRP3 compromises APP levels." (2021) Alzheimers Res Ther. 2021 Nov 2;13(1):181 / PMID: 34727970 PMCID: PMC8565065 DOI: 10.1186/s13195-021-00921-5
15. Delicado-Miralles, Miguel, Enrique Velasco, Ariadna Díaz-Tahoces, Juana Gallar, M. Carmen Acosta and Adolfo Aracil-Marco"Deciphering the Action of Perfluorohexyloctane Eye Drops to Reduce Ocular Discomfort and Pain." (2021) Front. Med., 26 October 2021 | https://doi.org/10.3389/fmed.2021.709712
16. De Andrés, J., Navarrete-Rueda, F., Fabregat, G., García-Gutiérrez, M.S., Monsalve-Dolz, V., Harutyunyan, A., Mínguez-Martí, A., Rodriguez-Lopez, R., Manzanares, J. Differences in Gene Expression of Endogenous Opioid Peptide Precursor, Cannabinoid 1 and 2 Receptors and Interleukin Beta in Peripheral Blood Mononuclear Cells of Patients With Refractory Failed Back Surgery Syndrome Treated With Spinal Cord Stimulation: Markers of Therapeutic Outcomes? (2021) Neuromodulation, 24 (1), pp. 49-60.
17. Dotti, C.; Rodríguez V.; Patricia Boya; Ignacio Torres-Alemán; Coral Sanfeliu; Isabel Varela; Jesús Ávila; Mariano Carrión; Belén Peral; Sonia de Pascual-Teresa; Esther Nova; Fermina Rojo Pérez; Gloria Fernández-Mayoralas; Francisco Javier Moreno Fuentes; José V. Sanchez Mut; Alfonso Araque; Diego Sánchez González; Soledad Ballesteros Jiménez; Félix Hernández. Challenge 7: Aging and Brain Deterioration (pp 98-108) in book “White Paper 5: Brain, Mind and Behaviour” Ed: Consejo Superior de Investigaciones Científicas (CSIC).DOCUMENT TYPE: Book Chapter
18. Domínguez, María; Huertas, Pablo; Casado, Marta; López Atalaya Martínez, José Pascual; Pendás, Alberto M.; Montoliu, José Lluís; Ros, Marian. Chapter 1: Methods to analyse and modify the genome. (pp 10-27) in book “White Paper 3: Genome & Epigenetics “ Ed: Consejo Superior de Investigaciones Científicas (CSIC). DOCUMENT TYPE: Book Chapter
19. Fuentes-Ramos M, Alaiz-Noya M, Barco A. Transcriptome and epigenome analysis of engram cells: Next-generation sequencing technologies in memory research. (2021) Neurosci Biobehav Rev 127:865-875. doi: 10.1016/j.neubiorev.2021.06.010
20. Gasparyan, A.; Navarrete, F.; Manzanares, J. (2021) The administration of sertraline plus naltrexone reduces ethanol consumption and motivation in a long-lasting animal model of post-traumatic stress disorder. Neuropharmacology 189:108552
21. Gomez-Marin, A. Facing biology's open questions: Rupert Sheldrake's “heretical” hypothesis turns 40. (2021) BioEssays.
22. Gomez-Marin, A., Arnau, J. When the Part Mirrors the Whole: Interactions Beyond “Simple Location” (2021) Frontiers in Psychology, 11, art. no. 523885. OPEN ACCESS: All Open Access, Gold, Green
23. Herrero-Navarro A, Puche-Aroca L, Moreno-Juan V, Sempere-Ferràndez A, Espinosa A, Susín R, Torres-Masjoan L, Leyva-Díaz E, Karow M, Figueres-Oñate M, López-Mascaraque L, López-Atalaya JP, Berninger B, López-Bendito G. Astrocytes and neurons share region-specific transcriptional signatures that confer regional identity to neuronal reprogramming. (2021) Science Advances. 7(15):eabe8978
24. Juarez-Carreño S, DM Vallejo, M. Palomino-Schätzlein, P. Ramon-Cañellas, R. Santoro, J. Carranza-Valencia, E. de Hartog, D. Ferres-Marco, A. Romero, H. Payette Peterson, E. Ballesta-Illan, A. Pineda-Lucena, M. Domínguez*, J. Morante*. Body-Fat Sensor Triggers Ribosome Maturation in the Steroidogenic Gland to Initiate Sexual Maturation in Drosophila. Cell Reports 2021, 37:109830. *Co-corresponding authors.
25. Kitazawa, T., Machlab, D., Joshi, O., Maiorano, N., Kohler, H., Ducret, S., Kessler, S., Gezelius, H., Soneson, C., Papasaikas, P., López-Bendito, G., Stadler, M.B., Rijli, F.M. A unique bipartite Polycomb signature regulates stimulus-response transcription during development. (2021) Nature Genetics, 53 (3), pp. 379-391.
26. Lalueza-Fox, Carles; de la Torre, I.; Bastir, Markus; Borrell, V.; Díaz del Río, P.; Navarro, A.; Marqués-Bonet, T.; Vicent, J.M. Challenge 6: Social and human evolution. (pp 125-143) In book “White Paper 2: Origins, (Co)evolution, Diversity & Synthesis of Life” Ed: Consejo Superior de Investigaciones Científicas (CSIC) DOCUMENT TYPE: Book Chapter
27. Leroy, F., de Solis, C.A., Boyle, L.M. et al. Enkephalin release from VIP interneurons in the hippocampal CA2/3a region mediates heterosynaptic plasticity and social memory. Mol Psychiatry (2021). DOI: 10.1038/s41380-021-01124-y
28. Luna, C., Mizerska, K., Quirce, S., Belmonte, C., Gallar, J., Acosta, M.D.C., Meseguer, V. Sodium channel blockers modulate abnormal activity of regenerating nociceptive corneal nerves after surgical lesion. (2021) Investigative Ophthalmology and Visual Science, 62 (1), art. no. 2. OPEN ACCESS: All Open Access, Gold, Green
29. Luna C., Quirce S., Aracil-Marco A., Belmonte C., Gallar J., Acosta MC.Unilateral Corneal Insult Also Alters Sensory Nerve Activity in the Contralateral Eye. (2021) Front. Med., 15 November 2021 | https://doi.org/10.3389/fmed.2021.767967
30. Madrigal, M.P., Jurado, S. Specification of oxytocinergic and vasopressinergic circuits in the developing mouse brain. Commun Biol 4, 586 (2021). https://doi.org/10.1038/s42003-021-02110-4
31. Manzanero-Ortiz, S., de Torres-Jurado, A., Hernández-Rojas, R., Carmena, A. Pilot RNAi Screen in Drosophila Neural Stem Cell Lineages to Identify Novel Tumor Suppressor Genes Involved in Asymmetric Cell Division. (2021). Int. J. Mol. Sci. 22, 11332; doi.org/10.3390/ijms222111332
32. Martini FJ, Guillamón-Vivancos T, Moreno-Juan V, Valdeolmillos M, López-Bendito G. Spontaneous activity in developing thalamic and cortical sensory networks. Neuron. (2021) Aug 18;109(16):2519-2534. doi: 10.1016/j.neuron.2021.06.026. Epub 2021 Jul 21. PMID: 34293296; PMCID: PMC7611560.
33. Millán-Pascual, Rafael; Luis M. Martínez; Diego Alonso-Pablos; Manuel J. Blanco; Felipe Criado-BoadoMaterialidades, espacio, pensamiento: arqueología de la cognición visual. (2021) Trabajos de Prehistoria 78: 7-25
34. Mohammadi, P., Nilforoushzadeh, M.A., Youssef, K.K., Sharifi-Zarchi, A., Moradi, S., Khosravani, P., Aghdami, R., Taheri, P., Hosseini Salekdeh, G., Baharvand, H., Aghdami, N.Defining microRNA signatures of hair follicular stem and progenitor cells in healthy and androgenic alopecia patients.(2021) Journal of Dermatological Science, 101 (1), pp. 49-57.
35. Murillo, A.; Navarro, A.I.; Puelles, E.; Zhang, Y.; Petros, T.J.; Pérez-Otaño ITemporal Dynamics and Neuronal Specificity of Grin3a Expression in the Mouse Forebrain. (2021) Cerebral Cortex 31: 1914.
36. Navarrete, F.; García-Gutiérrez, M.S.; Gasparyan, A.; Austrich-Olivares, A.; Manzanares, J.Role of Cannabidiol in the Therapeutic Intervention for Substance Use Disorders. (2021) Frontiers in Pharmacology 12:626010. Review
37. Nieto MA. Are You Interested or Afraid of Working on EMT? (pp 19-28) In book “The Epithelial-to Mesenchymal Transition. Methods and Protocols”, Ed. Humana Press / Springer. DOCUMENT TYPE: Book Chapter
38. Ordás, P., Hernández-Ortego, P., Vara, H., Fernández-Peña, C., Reimúndez, A., Morenilla-Palao, C., Guadaño-Ferraz, A., Gomis, A., Hoon, M., Viana, F., Señarís, R. Expression of the cold thermoreceptor TRPM8 in rodent brain thermoregulatory circuits. (2021) Journal of Comparative Neurology, 529 (1), pp. 234-256.
39. Pallarésa, Vicente; Mateusz Dudekb; Andrea Morenoa; Úrsula Pérez-Ramírezc; David Moratalc; Mia Haaranenb; Roberto Ciccocioppod; Wolfgang H. Sommere; Santiago Canals; Petri HyytiäbNeuroimaging reveals functionally distinct neuronal networks associated with high-level alcohol consumption in two genetic rat models. (2021) Behavioural Pharmacology 32: 229-238
40. Planas, Anna M; Juan C. Moreno; Manuel Álvarez-Dolado; Sergio Casas-Tintó; Ángel Luís Corbí; Javier de las Rivas; Manuel Delgado; Manuel Fuentes-García; Elena González-Rey; Teresa Iglesias; Amadeu Llebaria; José P. López-Atalaya; María Mittelbrunn; Eduardo Rocon; Teresa Serrano; Rosa Villa; Alberto Yúfera; Esther Duarte; Ángel Gil-Agudo. CHALLENGE 8: BRAIN & SPINAL CORD DAMAGE & REHABILITATIO (pp 107-123) in book “White Paper 5: Brain, Mind and Behaviour” Ed: Consejo Superior de Investigaciones Científicas (CSIC) DOCUMENT TYPE: Book Chapter
41. Prieto-Colomina, Anna; Virginia Fernández; Kaviya Chinnappa; Víctor BorrellMiRNAs in early brain development and pediatric cancer: at he intersection between healthy and diseased embryonic development. (2021) BioEssays 43(7): e210073
42. Reig, RamónGABA B receptors: modulation of thalamocortical dynamics and synaptic plasticity. (2021) Neuroscience 456: 131-142. Review
43. Rueda-Carrasco J , Martin-Bermejo MJ, Pereyra G, Mateo MI, Borroto A, Brosseron F, Kummer MP, Schwartz S, López-Atalaya JP, Alarcon B, Esteve P, Heneka MT, Bovolenta P. SFRP1 modulates astrocyte-to-microglia crosstalk in acute and chronic neuroinflammation. (2021) EMBO Reports . 22(11):e51696
44. Sanchez-Vives, M.V., Barbero-Castillo, A., Perez-Zabalza, M., Reig, R. GABAB receptors: modulation of thalamocortical dynamics and synaptic plasticity. (2021) Neuroscience, 456, pp. 131-142. OPEN ACCESS: All Open Access, Hybrid Gold
45. Schwaller, F., Bégay, V., García-García, G., Taberner, F.J., Moshourab, R., McDonald, B., Docter, T., Kühnemund, J., Ojeda-Alonso, J., Paricio-Montesinos, R., Lechner, S.G., Poulet, J.F.A., Millan, J.M., Lewin, G.R. USH2A is a Meissner’s corpuscle protein necessary for normal vibration sensing in mice and humans. (2021) Nature Neuroscience, 24 (1), pp. 74-81.
46. Sotelo C.Cellular Mechanisms Involved in Cerebellar Microzonation. (2021) Neuroscience, 462(56-59). Review
47. Valbuena, S., Lerma, J. Kainate Receptors, Homeostatic Gatekeepers of Synaptic Plasticity.(2021) Neuroscience, 456, pp. 17-26.
48. Valbuena S, Lerma J. Losing balance: Kainate receptors and psychiatric disorders comorbidities. (2021) Neuropharmacology 191:108558.
49. Vigouroux Robin J;Karine Duroure;Juliette Vougny;Shahad Albadri;Peter Kozulin;Eloisa Herrera;Kim Nguyen-Ba-Charvet;Ingo Braasch;Rodrigo Suárez;Filippo Del Bene;Alain Chédotal. Bilateral visual projections exist in non-teleost bony fish and predate the emergence of tetrapods. Science. 372 ( 6538): 150-156
50. Villalba, A., Götz, M., Borrell, V. The regulation of cortical neurogenesis. (2021) Current Topics in Developmental Biology, 142, pp. 1-66. DOCUMENT TYPE: Book Chapter
51. Viudes-Sarrion, N., Velasco, E., Delicado-Miralles, M., Lillo-Navarro, C. Static magnetic stimulation in the central nervous system: a systematic review (2021) Neurological Sciences, 42(5):1733-1749
52. Wagstaff, L.J., Gomez-Sanchez, J.A., Fazal, S.V., Otto, G.W., Kilpatrick, A.M., Michael, K., Wong, L.Y.N., Ma, K.H., Turmaine, M., Svaren, J., Gordon, T., Arthur-Farraj, P., Velasco-Aviles, S., Cabedo, H., Benito, C., Mirsky, R., Jessen, K.R., Chao, M.V. Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring schwann cell c-jun.(2021) eLife, 10, art. no. e62232, pp. 1-32. OPEN ACCESS: All Open Access, Gold, Green.
53. Ximenis, M., Mulet, J., Sala, S., Sala, F., Criado, M., González-Muñiz, R., de Vega, MJP. Natural polyhydroxy flavonoids, curcuminoids, and synthetic curcumin analogs as a7 nAChRs positive allosteric modulators. (2021) International Journal of Molecular Sciences, 22 (2), art. no. 973, pp. 1-17. OPEN ACCESS: All Open Access, Gold, Green.