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People About the institute Angela Nieto
1982 – B. Sci. in Biology, Universidad Autónoma de Madrid, Spain

Ph.D program:
1987.- Ph.D. in Biochemistry and Molecular Biology. Universidad Autónoma de Madrid, Spain

Posdoctoral Positions:
Sept 1991- Dec 1992  Associate research scientist at the National Institute for Medical Research. London (UK).
July 1989- Aug 1991  Postdoc at  the National Institute for Medical Research. London (UK).
1988-June 1989 Postdoc at Centre for Biomedical Research Alberto Sols, CSIC-UAM, Madrid.

Previous positions:
- 2004 Full Professor and Head of Department at the Cajal Institute, Madrid
- August 2000 -2003 Associate Professor at the Cajal Institute, Madrid.  
- Jan 1993 - July 2000 Assistant Professor and Group Leader at the Cajal Institute, Madrid
- 2011-2014. Vice-chair of the European Molecular Biology Conference (EMBC).
- 2008-2013. President of the Scientific Board for Courses at International University Menéndez Pelayo (Valencia)
- 2004-2012. Member of the Advisory Board for Chief Editor at EMBO Publications
- 2012. Member of Committee for tercentennial celebration of the Spanish National Library
- 2004-2010 Member of Faculty of 1000 (Developmental Biology)
- 2005-2009 Member of the EMBO Committee for Publications and Electronic Information
- 2006-2009 Member of the Scientific Committee for the Genome Project Spain
- 2004-2008 Associate Editor of Developmental Dynamics
- 2004-2008 Member of the Executive Committee of the Spanish Research Council (CSIC)
- 2004-2007 Member of the FEBS fellowships Committee.
- 2003-2006 Committee Member for Ethics and Animal Experimentation of the Spanish Research Council (CSIC)
- 2000-2004 Treasurer of the Spanish Society for Biochemistry and Molecular Biology
- 1995-2006  Executive Committee Member Spanish Society for Developmental Biology

Current Position:
2004- Full Professor and Head of Developmental Neurobiology (2005-) at Instituto de Neurociencias, CSIC-UMH, Alicante
- President of the Spanish Society of Developmental Biology (SEBD)
- Spanish Scientific Delegate for the European Molecular Biology laboratory (EMBL) and the European Molecular Biology Conference (EMBC). Vice-chair of EMBL
- Member of the Board of Directors of the International Society of Differentiation
- Member of the European Molecular Biology Organization (EMBO)
- Member of the Academy of Europe (Academia Europaea)
- Past-President of the EMT International Association (TEMTIA).
- Member of CONCYTEC. Permanent Research and Technology Council of the Government of Valencia.
- Member of ACCGV. High Advisory Council of the Valencian Government.
- Member of Scientific Advisory Committee (SAC) of
- Member of SAC for:
* The National Center for Oncological Research (CNIO), Madrid
* Center for Genomic Regulation (CRG), Barcelona
* Institute of Functional Genomics, Lyon, France
* Institut de Biologie du Développement de Marseille (IBDML) Marseille, France
* Ramón y Cajal Hospital, Madrid
* “Centro de Ciencias de Benasque Pedro Pascual”
* Biomedical Research Institute “IDIBELL” Barcelona
* Andalusian Centre for Developmental Biology (CABD). Seville.
-Editorial Board member for EMBO J, EMBO reports, Trends in Genetics; Current Opinion in Genetics and Development, Mechanisms of Development, Gene Expression Patterns and Int. J. Dev. Biol.

Research Fields:
We are interested in the analysis of cell movements and cell plasticity in health and disease. Our group studies the regulation of epithelial-mesenchymal transitions (EMT) during vertebrate embryonic development and in several pathologies including cancer and fibrosis.

Representative Publications

Acloque, H. , Ocaña, O.H., Matheu, A., Rizzoti, K., Wise,C., Lovell-Badge, R. and Nieto, M.A. " Reciprocal repression between Sox3 and Snail transcription factors defines embryonic territories at gastrulation. " Dev. Cell . 21 , 546 - 558 ( 2011 )

Ocaña OH. , Córcoles, R., Fabra, A., Moreno-Bueno, G., Acloque, H., Vega, S., Barrallo-Gimeno, A., Cano, A. and Nieto, M.A. " Metastatic colonization requires the repression of the epithelial-mesenchymal transition inducer Prrx1. " Cancer Cell . 22 , 709 - 724 ( 2012 )

Mingot JM. , Vega S., Cano A., Portillo F. and Nieto MA. " eEF1A mediates the nuclear export of SNAG-containing proteins via the Exportin5-aatRNA complex. " Cell Rep . 5 , 727 - 737 ( 2013 )

Nieto MA. , " Epithelial plasticity: a common theme in embryonic and cancer cells. " Science . 342 , - 1234850 ( 2013 )

Grande M.T. , Sanchez-Laorden B.L., Lopez-Blau, C., De Frutos, C.A., Boutet, A., Rowe, G., Weiss, S. J., Lopez-Novoa, J.M. and Nieto, M.A. " Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease " Nat. Med . 21 , 989 - 997 ( 2015 )
Consejo Superior de Investigaciones Científicas
Universidad Miguel Hernández

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